Humalog and Epzicom drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Humalog (insulin lispro recombinant) and Epzicom (abacavir sulfate; lamivudine). Common drug interactions include osteonecrosis among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Humalog and Epzicom. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Humalog?
Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.
What is Epzicom?
Epzicom has active ingredients of abacavir sulfate; lamivudine. It is often used in hiv infection. eHealthMe is studying from 4,937 Epzicom users. Check the latest studies of Epzicom.
31 people who take Humalog and Epzicom together, and have interactions are studied.

What are the common drug interactions of Humalog and Epzicom, by gender? *:
female:
- Osteonecrosis (death of bone)
- Pneumonia
- Renal failure (kidney dysfunction)
- Skeletal injury (bone and supporting muscle injury)
- Stress
- Swelling
- Urinary tract infection
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chronic kidney disease
male:
- Chronic kidney disease
- Emotional distress
- Hyperkalaemia (damage to or disease of the kidney)
- Osteoporosis (bones weak and more likely to break)
- Proteinuria (presence of protein in the urine)
- Renal impairment (severely reduced kidney function)
- Bone density decreased
- Eating disorder
- Renal failure acute (rapid kidney dysfunction)
- Abasia (inability to walk)
What are the common drug interactions of Humalog and Epzicom, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Foot fracture
- Hyperkalaemia (damage to or disease of the kidney)
- Anaemia of chronic disease
- Bone density decreased
- Chronic kidney disease
- Emotional distress
- Hypertension (high blood pressure)
- Multiple fractures
- Nephropathy (damage to or disease of a kidney)
- Osteopenia (a condition where bone mineral density is lower than normal)
30-39:
n/a
40-49:
- Urinary tract infection
- Vitamin d deficiency
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chronic kidney disease
- Emotional distress
- Pain
- Renal injury (kidney injury)
- Bone density decreased
- Depression
50-59:
- Intermittent claudication
- Peripheral vascular disorder
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Pain
- Foot fracture
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Proteinuria (presence of protein in the urine)
- Sleep disorder
60+:
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Abasia (inability to walk)
- Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
- Haemophilic arthropathy (permanent joint disease)
- Hemiplegia (paralysis of one side of the body)
- Hypertension (high blood pressure)
- Ill-defined disorder
- Renal failure acute (rapid kidney dysfunction)
- Abdominal pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
What are the existing conditions these people have? *
- Panic Disorder: 6 people, 19.35%
- High Blood Pressure: 6 people, 19.35%
- Hepatitis C: 6 people, 19.35%
- Epididymitis (pain in the scrotum or testicle): 6 people, 19.35%
- Abdominal Pain Upper: 5 people, 16.13%
- Pain: 4 people, 12.90%
- Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 3 people, 9.68%
- Nausea And Vomiting: 2 people, 6.45%
- Insomnia (sleeplessness): 2 people, 6.45%
- High Blood Cholesterol: 2 people, 6.45%
* Approximation only. Some reports may have incomplete information.
Do you take Humalog and Epzicom?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Humalog and Epzicom:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Humalog:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Epzicom:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Humalog and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Epzicom and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on insulin lispro recombinant and abacavir sulfate; lamivudine (the active ingredients of Humalog and Epzicom, respectively), and Humalog and Epzicom (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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