Humalog and Methylcobalamin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Humalog (insulin lispro recombinant) and Methylcobalamin (vitamin b12). Common drug interactions include rotator cuff syndrome among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Humalog and Methylcobalamin. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

What is Methylcobalamin?

Methylcobalamin has active ingredients of vitamin b12. It is often used in vitamin b12 deficiency. eHealthMe is studying from 3,184 Methylcobalamin users. Check the latest studies of Methylcobalamin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

23 people who take Humalog and Methylcobalamin together, and have interactions are studied.

Humalog and Methylcobalamin drug interactions.

What are the common drug interactions of Humalog and Methylcobalamin, by gender? *:

female:

Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Hypertension (high blood pressure)
Eye disorder
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Cardiac failure chronic
Cerebral infarction (less blood supply to brain resulting tissue damage)
Diabetic foot
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Neuropathy peripheral (surface nerve damage)
Pneumonia

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertension (high blood pressure)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Intestinal perforation (complete penetration of the wall of the intestine)
Malignant anorectal neoplasm (cancerous tumour of anus or rectum)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Pain in extremity
Rash

What are the common drug interactions of Humalog and Methylcobalamin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Cardiac failure
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Eye disorder

60+:

Hypertension (high blood pressure)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Intestinal perforation (complete penetration of the wall of the intestine)
Malignant anorectal neoplasm (cancerous tumour of anus or rectum)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Urinary tract infection

What are the existing conditions these people have? *

Type 2 Diabetes: 4 people, 17.39%
Constipation: 4 people, 17.39%
Scleritis (inflammation of sclera): 2 people, 8.70%
Pulmonary Artery Thrombosis (blockage of the main artery of the lung): 2 people, 8.70%
Muscle Aches (muscle pain): 2 people, 8.70%
Microscopic Polyangiitis (inflammation involving multiple blood or lymph small-vessel): 2 people, 8.70%
Lipid Metabolism Disorder (genetic disorders are caused by errors in fatty acid metabolism): 2 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%
Gastritis Erosive (a break in the surface layer of the membrane lining the stomach with infection): 2 people, 8.70%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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