Humalog and Monoket drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Humalog (insulin lispro recombinant) and Monoket (isosorbide mononitrate). Common drug interactions include hypoglycaemia among females and hyperkalaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Humalog and Monoket. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

What is Monoket?

Monoket has active ingredients of isosorbide mononitrate. eHealthMe is studying from 623 Monoket users. Check the latest studies of Monoket.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

19 people who take Humalog and Monoket together, and have interactions are studied.

What are the common drug interactions of Humalog and Monoket, by gender? *:

female:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Arrhythmia (irregular heartbeat)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cough
Diabetes mellitus inadequate control
Diabetic coma
Head injury
Heart injury
Lower respiratory tract infection

male:

Hyperkalaemia (damage to or disease of the kidney)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Hallucination (an experience involving the perception of something not present)
Hospitalisation
Hypoglycaemia (deficiency of glucose in the bloodstream)
Psychomotor hyperactivity (feelings of extreme restlessness)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Humalog and Monoket, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Arrhythmia (irregular heartbeat)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cough
Diabetes mellitus inadequate control
Diabetic coma
Heart injury
Lower respiratory tract infection
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pulmonary congestion (congestion in the lungs)

60+:

Syncope (loss of consciousness with an inability to maintain postural tone)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Hypotension (abnormally low blood pressure)
Somnolence (a state of near-sleep, a strong desire for sleep)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cholecystitis (infection of gallbladder)
Confusional state
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 31.58%
Stable Angina (a constant chest pain): 2 people, 10.53%
Pain: 2 people, 10.53%
Neuropathy Peripheral (surface nerve damage): 2 people, 10.53%
Chest Pain: 2 people, 10.53%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 10.53%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 10.53%
Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 5.26%
High Blood Cholesterol: 1 person, 5.26%
Cardiac Disorder: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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