Humalog and Naltrexone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Humalog (insulin lispro recombinant) and Naltrexone (naltrexone). Common drug interactions include sjogren's syndrome among females and dysuria among males.

The phase IV clinical study analyzes what interactions people have when they take Humalog and Naltrexone. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,835 Naltrexone users. Check the latest studies of Naltrexone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

31 people who take Humalog and Naltrexone together, and have interactions are studied.

Humalog and Naltrexone drug interactions.

What are the common drug interactions of Humalog and Naltrexone, by gender? *:

female:

Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Back pain
Bipolar disorder (mood disorder)
Disability
Dry mouth
Epigastric discomfort
Gastric ulcer (stomach ulcer)
Gastritis (inflammation of stomach)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Abdominal discomfort

male:

Dysuria (painful or difficult urination)
Pain in extremity
Cardiac disorder
Oedema peripheral (superficial swelling)
Peripheral swelling
Suicidal ideation

What are the common drug interactions of Humalog and Naltrexone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal discomfort
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Influenza
Insomnia (sleeplessness)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Sputum discoloured
Urinary tract infection
Vulvovaginal mycotic infection (vulvovaginal fungal infection)

60+:

Pain in extremity
Alopecia (absence of hair from areas of the body)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Parkinson's disease
Renal artery stenosis (narrowing of renal artery)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 35.48%
Immunodeficiency Common Variable: 6 people, 19.35%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 4 people, 12.90%
Type 2 Diabetes: 3 people, 9.68%
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls): 2 people, 6.45%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 6.45%
Haemochromatosis (body to absorb more iron than usual from food): 2 people, 6.45%
Heart Disease: 2 people, 6.45%
High Blood Cholesterol: 2 people, 6.45%
High Blood Pressure: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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