Humalog and Sudafed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Humalog (insulin lispro recombinant) and Sudafed (pseudoephedrine hydrochloride). Common drug interactions include folliculitis among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Humalog and Sudafed. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

What is Sudafed?

Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion. eHealthMe is studying from 12,944 Sudafed users. Check the latest studies of Sudafed.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

55 people who take Humalog and Sudafed together, and have interactions are studied.

What are the common drug interactions of Humalog and Sudafed, by gender? *:

female:

Folliculitis (infection of hair root)
Infection
Injection site erythema (redness at injection site)
Kidney infection
Leukaemia (blood or bone marrow cancer)
Lymphadenopathy (disease or enlargement of lymph nodes)
Migraine (headache)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Necrosis (the death of body tissue)

male:

Dehydration (dryness resulting from the removal of water)
Blood glucose increased
Pulmonary artery stenosis congenital (congenital -narrowing (stenosis) that occurs in the lung artery)
Respiratory distress (difficulty in breathing)
Speech disorder developmental
Tachypnoea (a condition of rapid breathing over 20 per minute)
Blood sodium decreased
Diarrhoea
Ketoacidosis (high concentrations of ketone bodies in blood)
Blood bicarbonate decreased

What are the common drug interactions of Humalog and Sudafed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Diarrhoea
Blood glucose fluctuation
Blood ketone body present
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Large intestinal haemorrhage (bleeding in large intestine)
Malaise (a feeling of general discomfort or uneasiness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pyrexia (fever)
Social problem
Gastroenteritis (inflammation of stomach and intestine)

20-29:

n/a

30-39:

Tongue discolouration (colour change of tongue)

40-49:

Necrosis (the death of body tissue)
Perirectal abscess
Tooth abscess (pus formation in tooth)
Abdominal distension
Accident
Activities of daily living impaired
Anal abscess
Anxiety
Blood potassium decreased
Blood pressure decreased

50-59:

Headache (pain in head)
Cellulitis (infection under the skin)
Cough
Diarrhoea
Drug hypersensitivity
Ear infection
Folliculitis (infection of hair root)
Infection
Injection site bruising
Injection site erythema (redness at injection site)

60+:

Cardiac failure congestive
Febrile neutropenia (fever with reduced white blood cells)
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Myocarditis (inflammation of heart muscle myocardium)
Myositis (inflammation of the muscles)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Vascular occlusion (sudden blockage of a blood vessel, usually with a clot)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 10 people, 18.18%
Depression: 10 people, 18.18%
Mood Swings (an extreme or rapid change in mood): 8 people, 14.55%
Stress And Anxiety: 4 people, 7.27%
Nausea (feeling of having an urge to vomit): 4 people, 7.27%
Dehydration (dryness resulting from the removal of water): 4 people, 7.27%
Pain: 3 people, 5.45%
Multiple Myeloma (cancer of the plasma cells): 3 people, 5.45%
High Blood Pressure: 3 people, 5.45%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Humalog and Sudafed?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously