Humira and Copaxone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Humira (adalimumab) and Copaxone (glatiramer acetate). Common drug interactions include abasia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Humira and Copaxone. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.

What is Copaxone?

Copaxone has active ingredients of glatiramer acetate. It is often used in multiple sclerosis. eHealthMe is studying from 56,931 Copaxone users. Check the latest studies of Copaxone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

50 people who take Humira and Copaxone together, and have interactions are studied.

What are the common drug interactions of Humira and Copaxone, by gender? *:

female:

Abasia (inability to walk)
Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)
Arthralgia (joint pain)
Back pain
Benign neoplasm of bladder (benign (non-cancerous) tumours of the bladder)
Blood glucose increased
Blood pressure systolic decreased
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Confusional state

male:

Drug ineffective
Arthralgia (joint pain)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Device dislocation
Eye movement disorder
Fungal infection
Hyperthyroidism (over activity of the thyroid gland)
Joint crepitation
Joint swelling
Localised oedema (fluid retention in a particular part of the body)

What are the common drug interactions of Humira and Copaxone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blindness
Optic neuritis (optic nerve inflammation)
Prostate cancer
Abdominal pain
Fistula discharge (discharge from abnormal passage of structure/organ)
Diplopia (double vision)
Eye movement disorder
Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

20-29:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Injection site pain
Lung disorder (lung disease)
Neoplasm malignant (cancer tumour)
Pneumonia
Unresponsive to stimuli

30-39:

Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hypoaesthesia (reduced sense of touch or sensation)
Neoplasm malignant (cancer tumour)
Pancreatic carcinoma (pancreatic cancer)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sensory disturbance (sense disturbance)
Spleen disorder (disease of spleen)
Thyroid cancer

40-49:

Blood glucose increased
Blood pressure systolic decreased
Cough
Cystitis erosive (inflammation of the wall of the bladder causing erosion)
Dehydration (dryness resulting from the removal of water)
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Erythema (redness of the skin)
Fall
Feeding disorder (when children refuse to eat certain food groups)
Fluid retention (an abnormal accumulation of fluid in the blood)

50-59:

Constipation
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Abdominal pain upper
Anaphylactic reaction (serious allergic reaction)
Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)
Back pain
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Confusional state

60+:

Injection site pain
Activities of daily living impaired
Hyperventilation
Loss of consciousness
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Muscle disorder (muscle disease)
Muscle spasms (muscle contraction)
Screaming (a long loud piercing cry)
Sensation of heaviness
Spinal disorder (disease of spine a back bone)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 28.00%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 7 people, 14.00%
Pain: 6 people, 12.00%
Insomnia (sleeplessness): 5 people, 10.00%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 8.00%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 8.00%
Oedema (fluid collection in tissue): 4 people, 8.00%
High Blood Pressure: 4 people, 8.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 8.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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