Humira and Dramamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Humira (adalimumab) and Dramamine (dimenhydrinate). Common drug interactions include loss of consciousness among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Humira and Dramamine. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.

What is Dramamine?

Dramamine has active ingredients of dimenhydrinate. It is often used in motion sickness. eHealthMe is studying from 1,386 Dramamine users. Check the latest studies of Dramamine.



On Jul, 09, 2026

34 people who take Humira and Dramamine together, and have interactions are studied.

Humira and Dramamine drug interactions.

What are the common drug interactions of Humira and Dramamine, by gender? *:

female:

  1. Loss of consciousness
  2. Lymphoedema (localized fluid retention and tissue swelling)
  3. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  4. Nervousness
  5. Oropharyngeal pain
  6. Pulmonary embolism (blockage of the main artery of the lung)
  7. Sinus disorder (disease of sinus)
  8. Spondylitis (an inflammation of the vertebra with spinal cord involvement)
  9. Abdominal pain upper
  10. Accidental exposure

male:

  1. Rash
  2. Anal fissure
  3. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  4. Muscle spasms (muscle contraction)
  5. Pain in extremity
  6. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  7. Purulent discharge (discharge that contains pus)
  8. Road traffic accident
  9. Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Humira and Dramamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Injection site pain
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Drug dependence
  4. Suicidal ideation

20-29:

n/a

30-39:

  1. Purulent discharge (discharge that contains pus)
  2. Road traffic accident
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Splenic rupture
  5. Urinary tract infection
  6. Cardiac disorder
  7. Cushing's syndrome (obesity, a rounded face, increased fat)
  8. Loss of consciousness
  9. Lymphoedema (localized fluid retention and tissue swelling)
  10. Peripheral swelling

40-49:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Depressed mood
  4. Depression
  5. Hot flush (sudden feelings of heat)
  6. Hypersomnia (excessive daytime sleepiness (eds))
  7. Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
  8. Petit mal epilepsy (absence seizure)
  9. Premature menopause
  10. Road traffic accident

50-59:

  1. Pain
  2. Injection site pain
  3. Fatigue (feeling of tiredness)
  4. Chills (felling of cold)
  5. Drug ineffective
  6. Gastrointestinal infection (infection of stomach and intestine)
  7. Gastrointestinal inflammation (inflammation of stomach and intestine)
  8. Haematochezia (passage of stools containing blood)
  9. Hospitalisation
  10. Intestinal obstruction

60+:

  1. Pain in extremity
  2. Rash
  3. Increased bronchial secretion
  4. Lung infection
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  7. Muscle rupture (tear in muscle)
  8. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  9. Peripheral swelling
  10. Pneumonia

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 15 people, 44.12%
  2. Depression: 11 people, 32.35%
  3. Pain: 10 people, 29.41%
  4. Nausea (feeling of having an urge to vomit): 10 people, 29.41%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 17.65%
  6. Gastric Disorder (disease of stomach): 6 people, 17.65%
  7. High Blood Cholesterol: 6 people, 17.65%
  8. High Blood Pressure: 6 people, 17.65%
  9. Sleep Disorder: 4 people, 11.76%
  10. Joint Pain: 4 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Humira and Dramamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dramamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Humira and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dramamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on adalimumab and dimenhydrinate (the active ingredients of Humira and Dramamine, respectively), and Humira and Dramamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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