Humira and Fungizone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Humira (adalimumab) and Fungizone (amphotericin b). Common drug interactions include mycosis fungoides among females and colitis among males.
The phase IV clinical study analyzes what interactions people have when they take Humira and Fungizone. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Humira?
Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.
What is Fungizone?
Fungizone has active ingredients of amphotericin b. eHealthMe is studying from 4,456 Fungizone users. Check the latest studies of Fungizone.
11 people who take Humira and Fungizone together, and have interactions are studied.

What are the common drug interactions of Humira and Fungizone, by gender? *:
female:
- Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin)
- Prurigo (chronic skin disease causing severe itching)
- Psoriasis (immune-mediated disease that affects the skin)
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
- Bladder cancer recurrent
- Pustular psoriasis (raised bumps on the skin that are filled with pus)
- Activities of daily living impaired
- Acute respiratory failure
- Antimitochondrial antibody positive
- Antineutrophil cytoplasmic antibody positive
male:
- Colitis (inflammation of colon)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Acute respiratory distress syndrome
- Blood creatinine increased
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Hypotension (abnormally low blood pressure)
- Meningitis cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
- Pneumonia bacterial (pneumonia associated with bacterial infection)
- Pneumonia cryptococcal (pneumonia caused by cryptococcal infection)
- Pulmonary mass
What are the common drug interactions of Humira and Fungizone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Colitis (inflammation of colon)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Hypocapnia (level of carbon dioxide in the blood is lower than normal)
- Hypoxia (low oxygen in tissues)
- Irritable bowel syndrome
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
30-39:
- Pustular psoriasis (raised bumps on the skin that are filled with pus)
40-49:
- Bladder cancer recurrent
50-59:
- Acute respiratory distress syndrome
- Blood creatinine increased
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Hypotension (abnormally low blood pressure)
- Meningitis cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
- Pneumonia bacterial (pneumonia associated with bacterial infection)
- Pneumonia cryptococcal (pneumonia caused by cryptococcal infection)
- Pulmonary mass
- Pulmonary oedema (fluid accumulation in the lungs)
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
60+:
- Mycosis fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin)
- Prurigo (chronic skin disease causing severe itching)
- Balance disorder
- Biliary cirrhosis (biliary cirrhosis occurs due to obstruction to the flow of bile through bile ducts either within the liver or outside the liver)
- Blood corticotrophin decreased
- Blood cortisol decreased
- Cerebral small vessel ischaemic disease (inadequate blood supply to small blood vessel of brain)
- Clostridial infection (infectious conditions by clostridium bacteria)
- Diplopia (double vision)
- Drug ineffective
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 27.27%
- Sapho Syndrome (a disorder involving the skin, bone, and joints): 2 people, 18.18%
- Psoriasis (immune-mediated disease that affects the skin): 2 people, 18.18%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 9.09%
- Meningitis Cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 1 person, 9.09%
- Clostridial Infection (infectious conditions by clostridium bacteria): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Humira and Fungizone?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Humira and Fungizone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Humira:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Fungizone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Humira and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fungizone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on adalimumab and amphotericin b (the active ingredients of Humira and Fungizone, respectively), and Humira and Fungizone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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