Humira and Oxervate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Humira (adalimumab) and Oxervate (cenegermin-bkbj). Common drug interactions include eye pain among females and eye pain among males.
The phase IV clinical study analyzes what interactions people have when they take Humira and Oxervate. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Humira?
Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.
What is Oxervate?
Oxervate has active ingredients of cenegermin-bkbj. eHealthMe is studying from 7,219 Oxervate users. Check the latest studies of Oxervate.
35 people who take Humira and Oxervate together, and have interactions are studied.

What are the common drug interactions of Humira and Oxervate, by gender? *:
female:
- Eye pain
- Headache (pain in head)
- Influenza
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Respiratory syncytial virus infection (viral disease of respiratory system)
- Cough
- Facial pain
- Weight decreased
- Eye swelling
- Hospitalisation
male:
- Eye pain
- Death
- Muscle spasms (muscle contraction)
- Neuralgia (pain in one or more nerves)
- Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
- Pain
- Pain in extremity
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Vision blurred
- Visual impairment
What are the common drug interactions of Humira and Oxervate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Headache (pain in head)
- Eye pain
- Influenza
- Respiratory syncytial virus infection (viral disease of respiratory system)
- Eye abscess
- Herpes ophthalmic (eye infection caused by herpes simplex virus (hsv))
- Vision blurred
60+:
- Eye pain
- Cough
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Pneumonia
- Rhinorrhoea (watery mucus discharge from the nose)
- Ulcerative keratitis (ulcerative inflammation of the cornea)
- Visual impairment
- Death
- Corneal disorder
- Photophobia (extreme sensitivity to light)
What are the existing conditions these people have? *
- Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 31 people, 88.57%
- Ulcerative Keratitis (ulcerative inflammation of the cornea): 6 people, 17.14%
- Hypoaesthesia Eye (reduced sense of touch or sensation on eyes): 6 people, 17.14%
- Keratitis (eye's cornea, the front part of the eye, becomes inflamed): 2 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Humira and Oxervate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Humira and Oxervate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Humira:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Oxervate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Humira and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oxervate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on adalimumab and cenegermin-bkbj (the active ingredients of Humira and Oxervate, respectively), and Humira and Oxervate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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