Humira and Sectral drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Humira (adalimumab) and Sectral (acebutolol hydrochloride). Common drug interactions include headache among females and lymphadenopathy among males.
The phase IV clinical study analyzes what interactions people have when they take Humira and Sectral. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.
What is Humira?
Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.
What is Sectral?
Sectral has active ingredients of acebutolol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 3,548 Sectral users. Check the latest studies of Sectral.
42 people who take Humira and Sectral together, and have interactions are studied.

What are the common drug interactions of Humira and Sectral, by gender? *:
female:
- Headache (pain in head)
- Arthralgia (joint pain)
- Colorectal cancer metastatic (cancer of colon and rectal spreads to other parts)
- Coronary artery stenosis (narrowing of coronary artery)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Drug ineffective
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Lung disorder (lung disease)
- Lung infection
- Neuropathy peripheral (surface nerve damage)
male:
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Lymphoid tissue hyperplasia (a rapid increase in the number of normal cells (called lymphocytes) that are contained in lymph nodes)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
What are the common drug interactions of Humira and Sectral, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Lymphoid tissue hyperplasia (a rapid increase in the number of normal cells (called lymphocytes) that are contained in lymph nodes)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Injection site erythema (redness at injection site)
- Injection site haematoma (localized swelling filled with blood at injection site)
- Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Rectal haemorrhage (bleeding from anus)
- Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls)
50-59:
- Oesophageal carcinoma (cancer tumour of oesophagus)
- Disease progression
- Fear of needles
- Headache (pain in head)
- Nasal disorder (diseases of nose)
- Nasal septum perforation (hole in nasal septum)
- Sinusitis (inflammation of sinus)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
60+:
- Cardiac failure congestive
- Abscess limb (limb infection)
- Lung infection
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Neuropathy peripheral (surface nerve damage)
- Pneumonia
- Adverse drug reaction
- Cardiac perforation (a hole in heart)
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Heart rate irregular
What are the existing conditions these people have? *
- High Blood Cholesterol: 7 people, 16.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 16.67%
- Cardiac Disorder: 7 people, 16.67%
- Psoriasis (immune-mediated disease that affects the skin): 6 people, 14.29%
- Folate Deficiency (lack of folic acid): 5 people, 11.90%
- Cardiac Failure Congestive: 5 people, 11.90%
- Palindromic Rheumatism (sudden and rapidly developing attacks of arthritis): 4 people, 9.52%
- Pain: 4 people, 9.52%
- Osteoporosis (bones weak and more likely to break): 4 people, 9.52%
- Diabetes: 4 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Humira and Sectral?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Humira and Sectral:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Humira:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sectral:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Humira and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sectral and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on adalimumab and acebutolol hydrochloride (the active ingredients of Humira and Sectral, respectively), and Humira and Sectral (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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