Hycodan and Lopressor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hycodan (homatropine methylbromide; hydrocodone bitartrate) and Lopressor (metoprolol tartrate). Common drug interactions include blood uric acid increased among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Hycodan and Lopressor. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Hycodan?

Hycodan has active ingredients of homatropine methylbromide; hydrocodone bitartrate. It is often used in cough. eHealthMe is studying from 769 Hycodan users. Check the latest studies of Hycodan.

What is Lopressor?

Lopressor has active ingredients of metoprolol tartrate. It is often used in high blood pressure. eHealthMe is studying from 33,152 Lopressor users. Check the latest studies of Lopressor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

24 people who take Hycodan and Lopressor together, and have interactions are studied.

Hycodan and Lopressor drug interactions.

What are the common drug interactions of Hycodan and Lopressor, by gender? *:

female:

Blood uric acid increased
Hyperkalaemia (damage to or disease of the kidney)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Renal cell carcinoma stage unspecified (kidney cancer in unknown stage)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Blood creatine increased
Blood creatinine increased
Capillary leak syndrome (capillary leaks plasma)
Delirium (wild excitement)

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Adenoma benign (non-cancerous tumour -secreting)
Ear disorder
Flushing (the warm, red condition of human skin)
Groin pain
Intervertebral disc displacement
Mitral valve incompetence (inefficient heart valve)
Myalgia (muscle pain)
Otitis externa (external ear infection)
Pelvic pain

What are the common drug interactions of Hycodan and Lopressor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)
Generalised oedema (swelling all over the body)
Hyperkalaemia (damage to or disease of the kidney)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Blood creatine increased
Blood creatinine increased
Capillary leak syndrome (capillary leaks plasma)
Leukopenia (less number of white blood cells in blood)
Malignant neoplasm progression (cancer tumour came back)

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Adenoma benign (non-cancerous tumour -secreting)
Ear disorder
Flushing (the warm, red condition of human skin)
Groin pain
Intervertebral disc displacement
Mitral valve incompetence (inefficient heart valve)
Myalgia (muscle pain)
Otitis externa (external ear infection)
Pelvic pain

What are the existing conditions these people have? *

Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 8 people, 33.33%
Pain: 4 people, 16.67%
Nausea (feeling of having an urge to vomit): 4 people, 16.67%
Pain In Extremity: 3 people, 12.50%
Osteoporosis (bones weak and more likely to break): 3 people, 12.50%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 3 people, 12.50%
Ascites (accumulation of fluid in the abdominal cavity): 3 people, 12.50%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 8.33%
Bone Marrow Conditioning Regimen: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Hycodan and Lopressor?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously