Hydramine and Methamphetamine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydramine (diphenhydramine hydrochloride) and Methamphetamine hydrochloride (methamphetamine hydrochloride). Common drug interactions include drug toxicity among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Hydramine and Methamphetamine hydrochloride. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Methamphetamine hydrochloride?

Methamphetamine hydrochloride has active ingredients of methamphetamine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,434 Methamphetamine hydrochloride users. Check the latest studies of Methamphetamine hydrochloride.



On Jul, 08, 2026

26 people who take Hydramine and Methamphetamine hydrochloride together, and have interactions are studied.

Hydramine and Methamphetamine hydrochloride drug interactions.

What are the common drug interactions of Hydramine and Methamphetamine Hydrochloride, by gender? *:

female:

  1. Drug toxicity
  2. Pulmonary oedema (fluid accumulation in the lungs)
  3. Accidental death
  4. Adverse event
  5. Drowning (process of experiencing respiratory impairment from submersion/immersion in liquid)
  6. Drug dependence
  7. Drug diversion
  8. Foaming at mouth (excess saliva secretion)
  9. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  10. Overdose

male:

  1. Cardiac arrest
  2. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  3. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  4. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  5. Periodic limb movement disorder
  6. Pulmonary congestion (congestion in the lungs)
  7. Pulmonary oedema (fluid accumulation in the lungs)
  8. Respiratory depression (respiration has a rate below 12 breaths)
  9. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  10. Unresponsive to stimuli

What are the common drug interactions of Hydramine and Methamphetamine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Drug toxicity
  2. Pulmonary oedema (fluid accumulation in the lungs)
  3. Accidental death
  4. Cardiac arrest
  5. Drug dependence
  6. Drug diversion
  7. Foaming at mouth (excess saliva secretion)
  8. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  9. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  10. Theft

30-39:

  1. Pulmonary oedema (fluid accumulation in the lungs)
  2. Respiratory depression (respiration has a rate below 12 breaths)
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  5. Drowning (process of experiencing respiratory impairment from submersion/immersion in liquid)
  6. Overdose
  7. Pulmonary congestion (congestion in the lungs)

40-49:

  1. Cardiac arrest
  2. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

50-59:

  1. Adverse event
  2. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  3. Periodic limb movement disorder
  4. Unresponsive to stimuli

60+:

n/a

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydramine and Methamphetamine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methamphetamine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydramine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methamphetamine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride and methamphetamine hydrochloride (the active ingredients of Hydramine and Methamphetamine hydrochloride, respectively), and Hydramine and Methamphetamine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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