Hydramine and Viracept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydramine (diphenhydramine hydrochloride) and Viracept (nelfinavir mesylate). Common drug interactions include emotional distress among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Hydramine and Viracept. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Viracept?

Viracept has active ingredients of nelfinavir mesylate. It is often used in hiv infection. eHealthMe is studying from 6,399 Viracept users. Check the latest studies of Viracept.



On Jul, 29, 2026

25 people who take Hydramine and Viracept together, and have interactions are studied.

Hydramine and Viracept drug interactions.

What are the common drug interactions of Hydramine and Viracept, by gender? *:

female:

  1. Emotional distress
  2. Pain
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Ankle fracture
  5. Anxiety
  6. Depression
  7. Bone density decreased
  8. Chronic kidney disease
  9. Fibula fracture
  10. Foot fracture

male:

  1. Emotional distress
  2. Pain
  3. Bone density decreased
  4. Renal failure (kidney dysfunction)
  5. Gait disturbance
  6. Mobility decreased (ability to move is reduced)
  7. Osteoporosis (bones weak and more likely to break)
  8. Post-traumatic stress disorder
  9. Rash erythematous (redness of the skin)
  10. Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

What are the common drug interactions of Hydramine and Viracept, by age (0-1 to 60+)? *:

0-1:

  1. Death
  2. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Rash erythematous (redness of the skin)
  2. Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  3. Folliculitis (infection of hair root)
  4. Headache (pain in head)
  5. Lip ulceration (ulcer of lip)
  6. Mouth ulceration (mouth ulcers)
  7. Photophobia (extreme sensitivity to light)
  8. Rash papular (redness with papule)
  9. Skin nodule (slightly elevated lesions on or in the skin)
  10. Swelling

40-49:

  1. Back pain
  2. Chronic kidney disease
  3. Gait disturbance
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Nephropathy (damage to or disease of a kidney)
  6. Pain in extremity
  7. Renal failure (kidney dysfunction)
  8. Hepatic steatosis (fatty liver disease)
  9. Pruritus (severe itching of the skin)
  10. Rash

50-59:

  1. Emotional distress
  2. Pain
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Bone density decreased
  6. Chronic kidney disease
  7. Fibula fracture
  8. Mobility decreased (ability to move is reduced)
  9. Osteoporosis (bones weak and more likely to break)
  10. Renal impairment (severely reduced kidney function)

60+:

  1. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  2. Back pain
  3. Gamma-glutamyltransferase increased
  4. Horner's syndrome (horner syndrome is a disorder that affects the eye and surrounding tissues on one side of the face and results from paralysis of certain nerves)
  5. Renal failure (kidney dysfunction)
  6. Obesity (having too much body fat)
  7. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  8. Weight increased
  9. Bone density decreased
  10. Chronic kidney disease

What are the existing conditions these people have? *

  1. Hypersensitivity: 5 people, 20.00%
  2. Depression: 5 people, 20.00%
  3. Pain: 4 people, 16.00%
  4. High Blood Pressure: 4 people, 16.00%
  5. High Blood Cholesterol: 4 people, 16.00%
  6. Diabetes: 4 people, 16.00%
  7. Cardiac Disorder: 4 people, 16.00%
  8. Viral Infection: 3 people, 12.00%
  9. Urinary Retention (the inability to completely or partially empty the bladder): 3 people, 12.00%
  10. Indigestion: 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

Do you take Hydramine and Viracept?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydramine and Viracept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Viracept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydramine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viracept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride and nelfinavir mesylate (the active ingredients of Hydramine and Viracept, respectively), and Hydramine and Viracept (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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