Hydrea and Paraplatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrea (hydroxyurea) and Paraplatin (carboplatin). Common drug interactions include alopecia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrea and Paraplatin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrea?

Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 9,083 Hydrea users. Check the latest studies of Hydrea.

What is Paraplatin?

Paraplatin has active ingredients of carboplatin. eHealthMe is studying from 12,392 Paraplatin users. Check the latest studies of Paraplatin.

On Jul, 31, 2026

14 people who take Hydrea and Paraplatin together, and have interactions are studied.

Hydrea and Paraplatin drug interactions.

What are the common drug interactions of Hydrea and Paraplatin, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Anxiety
Depression
Hair colour changes
Hair disorder
Chills (felling of cold)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Malignant fibrous histiocytoma (a cancer tumour of uncertain origin that arises both in soft tissue and bone)
Nasopharyngitis (inflammation of the nasopharynx)

male:

Pneumonia
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dyspnoea exertional (breathlessness or shortness of breath)
Erythema (redness of the skin)
Hypersensitivity
Hypoxia (low oxygen in tissues)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Rash
Skin exfoliation (removal of the oldest dead skin cells)
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)

What are the common drug interactions of Hydrea and Paraplatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Neutropenia (an abnormally low number of neutrophils)
Pneumonia
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Malignant fibrous histiocytoma (a cancer tumour of uncertain origin that arises both in soft tissue and bone)
Malignant histiocytosis (cancerous increase in the number of immune cells)
Respiratory failure (excl neonatal) (inadequate gas exchange by the respiratory system(excluding neonatal))
Death
Febrile neutropenia (fever with reduced white blood cells)
Hemorrhagic tumour necrosis (death of body tissue with bleeding tumour)
Histiocytosis (a blood disease characterized by an abnormal multiplication of macrophages)

40-49:

Pneumonia
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Interstitial lung disease
Palpitations (feelings or sensations that your heart is pounding or racing)
Pyrexia (fever)
Dyspnoea exertional (breathlessness or shortness of breath)
Erythema (redness of the skin)
Hypersensitivity
Hypoxia (low oxygen in tissues)

50-59:

n/a

60+:

Alopecia (absence of hair from areas of the body)
Anxiety
Depression
Hair colour changes
Hair disorder
Failure to thrive (inadequate weight gain and physical growth in children)
Neutropenia (an abnormally low number of neutrophils)

What are the existing conditions these people have? *

Langerhans' Cell Granulomatosis: 5 people, 35.71%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 28.57%
Osteolysis (dissolution of bone): 3 people, 21.43%
Lung Neoplasm (tumour of lung): 3 people, 21.43%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.14%
Metastatic Squamous Cell Carcinoma (cancer of squamous cells spreads to other part): 1 person, 7.14%
Langerhans' Cell Histiocytosis: 1 person, 7.14%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 7.14%
Breast Cancer Female: 1 person, 7.14%
Breast Cancer: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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