Hydrea and Viagra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrea (hydroxyurea) and Viagra (sildenafil citrate). Common drug interactions include disorientation among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrea and Viagra. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrea?

Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 9,083 Hydrea users. Check the latest studies of Hydrea.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.



On Jul, 05, 2026

17 people who take Hydrea and Viagra together, and have interactions are studied.

Hydrea and Viagra drug interactions.

What are the common drug interactions of Hydrea and Viagra, by gender? *:

female:

  1. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  2. Ear discomfort
  3. Headache (pain in head)
  4. Metastases to bone (cancer spreads to bone)
  5. Oedema (fluid collection in tissue)
  6. Pain
  7. Discomfort
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Bile duct stone

male:

  1. Anaemia (lack of blood)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Night sweats (sweating in night)
  5. Red blood cell count decreased
  6. Skin ulcer
  7. White blood cell count decreased
  8. Drug ineffective
  9. Oedema (fluid collection in tissue)
  10. Blood cholesterol increased

What are the common drug interactions of Hydrea and Viagra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Cerebral artery thrombosis (clot formation in brain blood vessels)
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Chest pain
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Dyspnoea (difficult or laboured respiration)
  8. Emotional distress
  9. Fear of disease
  10. General physical health deterioration (weak health status)

20-29:

n/a

30-39:

  1. Oedema (fluid collection in tissue)

40-49:

  1. Bile duct stone

50-59:

  1. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  2. Ear discomfort
  3. Headache (pain in head)
  4. Metastases to bone (cancer spreads to bone)
  5. Oedema (fluid collection in tissue)
  6. Discomfort
  7. Pain

60+:

  1. Anaemia (lack of blood)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Night sweats (sweating in night)
  5. Red blood cell count decreased
  6. Skin ulcer
  7. White blood cell count decreased
  8. Blood cholesterol increased
  9. Death
  10. Drug ineffective

What are the existing conditions these people have? *

  1. Stress And Anxiety: 3 people, 17.65%
  2. Essential Thrombocythaemia (chronic blood cancer): 3 people, 17.65%
  3. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 17.65%
  4. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 11.76%
  5. Pain: 2 people, 11.76%
  6. Nausea (feeling of having an urge to vomit): 2 people, 11.76%
  7. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.76%
  8. Cor Pulmonale Chronic (long lasting enlargement of the right ventricle of the heart): 1 person, 5.88%
  9. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 5.88%
  10. Cough: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydrea and Viagra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Viagra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viagra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea and sildenafil citrate (the active ingredients of Hydrea and Viagra, respectively), and Hydrea and Viagra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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