Hydrochlorothiazide and Cataflam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrochlorothiazide (hydrochlorothiazide) and Cataflam (diclofenac potassium). Common drug interactions include mass among females and mental disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrochlorothiazide and Cataflam. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

What is Cataflam?

Cataflam has active ingredients of diclofenac potassium. It is often used in pain. eHealthMe is studying from 1,851 Cataflam users. Check the latest studies of Cataflam.

On Jul, 11, 2026

45 people who take Hydrochlorothiazide and Cataflam together, and have interactions are studied.

Hydrochlorothiazide and Cataflam drug interactions.

What are the common drug interactions of Hydrochlorothiazide and Cataflam, by gender? *:

female:

Mass
Multi-organ failure (multisystem organ failure)
Pericardial effusion (fluid around the heart)
Presyncope
Sinusitis (inflammation of sinus)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Tuberculin test positive
Uterine cancer
Vomiting
Appendicitis (inflammation of the appendix)

male:

Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Excessive eye blinking (excessive blinking is dry eyes)
Insomnia (sleeplessness)
Personality change
Post-traumatic stress disorder
Activities of daily living impaired
Agitation (state of anxiety or nervous excitement)
Balance disorder
Chills (felling of cold)

What are the common drug interactions of Hydrochlorothiazide and Cataflam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Menstruation irregular
Nausea (feeling of having an urge to vomit)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Pleural effusion (water on the lungs)
Polycystic ovaries (cysts in the ovaries that occurs when the follicle stops developing)
Pulmonary oedema (fluid accumulation in the lungs)
Renal cancer (cancer of kidney)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Subdural haemorrhage (bleeding between the skull and the surface of the brain)
Upper respiratory tract infection

30-39:

n/a

40-49:

Abdominal pain upper
Appendicitis (inflammation of the appendix)
Blood potassium decreased
Burning sensation
Gastric disorder (disease of stomach)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Swelling
Nasopharyngitis (inflammation of the nasopharynx)

50-59:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Anaphylactic reaction (serious allergic reaction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephropathy (damage to or disease of a kidney)
Rash
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Urticaria (rash of round, red welts on the skin that itch intensely)
Acute phosphate nephropathy (sudden damage to the kidneys caused by the formation of phosphate crystals)

60+:

Diarrhoea
Dizziness
Constipation
Decreased appetite
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dysphagia (a condition in which swallowing is difficult or painful)
Epistaxis (bleed from the nose)
Faecaloma (hard mass of fecal matter)
Haematocrit decreased
Haemoglobin decreased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 15.56%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.89%
Depression: 4 people, 8.89%
Sleep Disorder: 3 people, 6.67%
Renal Disorder (kidney disease): 3 people, 6.67%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 6.67%
Insomnia (sleeplessness): 3 people, 6.67%
Hypersensitivity: 3 people, 6.67%
High Blood Cholesterol: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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