Hydrocodone and Montelukast sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocodone (hydrocodone bitartrate; ibuprofen) and Montelukast sodium (montelukast sodium). Common drug interactions include pruritus among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocodone and Montelukast sodium. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

What is Montelukast sodium?

Montelukast sodium has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 26,093 Montelukast sodium users. Check the latest studies of Montelukast sodium.

On Jul, 06, 2026

93 people who take Hydrocodone and Montelukast sodium together, and have interactions are studied.

Hydrocodone and Montelukast sodium drug interactions.

What are the common drug interactions of Hydrocodone and Montelukast Sodium, by gender? *:

female:

Pruritus (severe itching of the skin)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Tricuspid valve incompetence (inefficient heart valve)
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Abdominal discomfort
Anaemia (lack of blood)
Angiotensin converting enzyme increased
Back pain
Cellulitis (infection under the skin)
Dizziness

male:

Constipation
Feeling hot
Fatigue (feeling of tiredness)
Limb injury
Obstruction
Oropharyngeal pain
Oxygen consumption increased
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia
Pneumonia bacterial (pneumonia associated with bacterial infection)

What are the common drug interactions of Hydrocodone and Montelukast Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Chronic fatigue syndrome (disorder that causes extreme fatigue)
Dehydration (dryness resulting from the removal of water)
Disability
Drug ineffective
Fall
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Hallucination (an experience involving the perception of something not present)
Headache (pain in head)

40-49:

Rhinitis allergic (inflammation of the nasal airways due to allergy)
Anaemia (lack of blood)
Angiotensin converting enzyme increased
Ankle fracture
Blood potassium decreased
Cluster headache (one-sided head pain with tearing)
Diastolic dysfunction
Dry eye (lack of adequate tears)
Dry mouth
Epstein-barr virus infection

50-59:

Blood pressure decreased
Blood pressure increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Cystitis (inflammation of the wall of the bladder)
Dysarthria (speech disorder)
Facial paralysis (loss of function of face muscle)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Cough
Pneumonia
Breath sounds
Constipation
Cystitis interstitial (unknown cause characterized by bladder pain)
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
Fall
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haemorrhage (bleeding)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 16 people, 17.20%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 16 people, 17.20%
Pain: 13 people, 13.98%
Immunodeficiency Common Variable: 12 people, 12.90%
High Blood Pressure: 12 people, 12.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 8.60%
Drowsiness: 8 people, 8.60%
Psoriasis (immune-mediated disease that affects the skin): 7 people, 7.53%
Primary Immunodeficiency Syndrome: 7 people, 7.53%
High Blood Cholesterol: 5 people, 5.38%

* Approximation only. Some reports may have incomplete information.

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