Hydrocodone and Viread drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocodone (hydrocodone bitartrate; ibuprofen) and Viread (tenofovir disoproxil fumarate). Common drug interactions include mobility decreased among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocodone and Viread. It is created by eHealthMe based on reports of 87 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

What is Viread?

Viread has active ingredients of tenofovir disoproxil fumarate. It is often used in hepatitis b. eHealthMe is studying from 51,542 Viread users. Check the latest studies of Viread.



On Jul, 10, 2026

87 people who take Hydrocodone and Viread together, and have interactions are studied.

Hydrocodone and Viread drug interactions.

What are the common drug interactions of Hydrocodone and Viread, by gender? *:

female:

  1. Mobility decreased (ability to move is reduced)
  2. Blood creatinine increased
  3. Renal impairment (severely reduced kidney function)
  4. Dysstasia (difficulty in standing)
  5. Lower limb fracture
  6. Nephrolithiasis (calculi in the kidneys)
  7. Renal failure (kidney dysfunction)
  8. Fatigue (feeling of tiredness)
  9. Asthenia (weakness)
  10. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)

male:

  1. Emotional distress
  2. Pain
  3. Gait disturbance
  4. Fatigue (feeling of tiredness)
  5. Renal impairment (severely reduced kidney function)
  6. Anaemia (lack of blood)
  7. Multiple fractures
  8. Renal injury (kidney injury)
  9. Spinal compression fracture (fracture due to spinal compression on bone)
  10. Back pain

What are the common drug interactions of Hydrocodone and Viread, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Depression
  4. Emotional distress
  5. Loss of employment
  6. Osteopenia (a condition where bone mineral density is lower than normal)
  7. Osteoporosis (bones weak and more likely to break)
  8. Pain
  9. Quality of life decreased
  10. Renal failure (kidney dysfunction)

30-39:

  1. Chronic kidney disease
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Emotional distress
  5. Pain
  6. Ankle fracture
  7. Asthenia (weakness)
  8. Back pain
  9. Dysstasia (difficulty in standing)
  10. Exercise tolerance decreased

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Chronic kidney disease
  6. Renal failure (kidney dysfunction)
  7. Bone density decreased
  8. Depression
  9. Fatigue (feeling of tiredness)
  10. Osteoporosis (bones weak and more likely to break)

50-59:

  1. Tibia fracture (fracture of lower leg bone)
  2. Urinary hesitation (difficulty in beginning the flow of urine)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Emotional distress
  6. Pain
  7. Osteoporosis (bones weak and more likely to break)
  8. Osteopenia (a condition where bone mineral density is lower than normal)
  9. Bone density decreased
  10. Renal failure (kidney dysfunction)

60+:

  1. Emotional distress
  2. Pain
  3. Bone loss
  4. Gait disturbance
  5. Osteonecrosis (death of bone)
  6. Spinal compression fracture (fracture due to spinal compression on bone)
  7. Abdominal pain
  8. Asthenia (weakness)
  9. Blood creatinine increased
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

  1. Hiv Infection: 82 people, 94.25%
  2. Pain: 15 people, 17.24%
  3. Stress And Anxiety: 12 people, 13.79%
  4. High Blood Pressure: 12 people, 13.79%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 12.64%
  6. Bacterial Infection: 11 people, 12.64%
  7. Depression: 10 people, 11.49%
  8. Inflammation: 8 people, 9.20%
  9. Fungal Infection: 8 people, 9.20%
  10. High Blood Cholesterol: 7 people, 8.05%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocodone and Viread?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydrocodone and Viread:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Viread:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viread and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydrocodone bitartrate; ibuprofen and tenofovir disoproxil fumarate (the active ingredients of Hydrocodone and Viread, respectively), and Hydrocodone and Viread (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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