Hydrocortisone and Atacand drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocortisone (hydrocortisone) and Atacand (candesartan cilexetil). Common drug interactions include pruritus among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocortisone and Atacand. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,426 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Atacand?

Atacand has active ingredients of candesartan cilexetil. It is often used in high blood pressure. eHealthMe is studying from 22,473 Atacand users. Check the latest studies of Atacand.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

81 people who take Hydrocortisone and Atacand together, and have interactions are studied.

Hydrocortisone and Atacand drug interactions.

What are the common drug interactions of Hydrocortisone and Atacand, by gender? *:

female:

Pruritus (severe itching of the skin)
Arthralgia (joint pain)
Pain
Platelet count decreased
Blood pressure fluctuation
Fatigue (feeling of tiredness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Stress
Weight decreased

male:

Asthenia (weakness)
Weight decreased
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hypotension (abnormally low blood pressure)
Sepsis (a severe blood infection that can lead to organ failure and death)
Anxiety
Arrhythmia (irregular heartbeat)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hepatic failure (liver failure)
Hypoaesthesia (reduced sense of touch or sensation)

What are the common drug interactions of Hydrocortisone and Atacand, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Rectal haemorrhage (bleeding from anus)
Weight increased
Weight decreased
Blood pressure fluctuation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Heart rate decreased
Renal failure (kidney dysfunction)
Chest pain
Back pain

50-59:

Diarrhoea
Drug level below therapeutic
Dyspnoea (difficult or laboured respiration)
Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
Hypersensitivity
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
Pyrexia (fever)
Rash
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Dyspnoea (difficult or laboured respiration)
Weight decreased
Dyspnoea exertional (breathlessness or shortness of breath)
Insomnia (sleeplessness)
Anaemia (lack of blood)
Asthenia (weakness)
Blood creatinine increased
Leukopenia (less number of white blood cells in blood)
Thrombocytopenia (decrease of platelets in blood)
Arthralgia (joint pain)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 16 people, 19.75%
Pain: 11 people, 13.58%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 7 people, 8.64%
Ankylosing Spondylitis (type of arthritis affecting the spine): 7 people, 8.64%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 7.41%
Osteoporosis (bones weak and more likely to break): 5 people, 6.17%
Neoplasm Of Thymus (tumour of thymus): 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and Atacand?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously