Hydrocortisone and Pimecrolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocortisone (hydrocortisone) and Pimecrolimus (pimecrolimus). Common drug interactions include eye pain among females and dermatitis atopic among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocortisone and Pimecrolimus. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Pimecrolimus?

Pimecrolimus has active ingredients of pimecrolimus. eHealthMe is studying from 1,358 Pimecrolimus users. Check the latest studies of Pimecrolimus.

On Jul, 08, 2026

75 people who take Hydrocortisone and Pimecrolimus together, and have interactions are studied.

Hydrocortisone and Pimecrolimus drug interactions.

What are the common drug interactions of Hydrocortisone and Pimecrolimus, by gender? *:

female:

Eye pain
Eyelid pain
Fall
Fibromyalgia (a long-term condition which causes pain all over the body)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gingival bleeding (bleeding gums)
Hand-foot-and-mouth disease
Head injury
Hordeolum (small collection of pus (abscess) on the eyelid)
Drug ineffective

male:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Anaphylactic reaction (serious allergic reaction)
Cardiac arrest
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dacryostenosis acquired (obstruction of the nasolacrimal duct-acquired)
Dyspepsia (indigestion)
Eye discharge
Eye irritation
Petechiae (a small red or purple spot caused by bleeding into the skin)

What are the common drug interactions of Hydrocortisone and Pimecrolimus, by age (0-1 to 60+)? *:

0-1:

Anaphylactic reaction (serious allergic reaction)

2-9:

Pneumonia
Pupil fixed
Pupillary reflex impaired
Rash
Skin reaction
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Surgery
Swelling
Varicella
Viral infection

10-19:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Abdominal hernia
Pneumonia
Sleep disorder
Therapeutic response decreased (less preventive response)

20-29:

Bone tuberculosis
Drug dependence

30-39:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Drug ineffective
Injection site erythema (redness at injection site)
Injection site mass
Injection site pain
Mouth ulceration (mouth ulcers)
Oral herpes (viral infection of mouth)
Rash
Sleep disorder
Blood alkaline phosphatase increased

40-49:

Drug ineffective
Psoriasis (immune-mediated disease that affects the skin)
Rebound effect (take-back effect)
Skin depigmentation (lightening of the skin)

50-59:

Allergy to arthropod sting
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Contusion (a type of hematoma of tissue in which capillaries)
Discomfort
Dry mouth
Dysgeusia (disorder of the sense of taste)
Dysphagia (a condition in which swallowing is difficult or painful)
Erythema (redness of the skin)
Headache (pain in head)
Muscle tightness

60+:

Erythema (redness of the skin)
Angular cheilitis (inflammation of one, or more commonly both, of the corners of the mouth)
Hordeolum (small collection of pus (abscess) on the eyelid)
Injection site pain
Pruritus (severe itching of the skin)
Rash pruritic (redness with itching)
Skin discolouration (change of skin colour)
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Dry skin
Eyelids pruritus (eyelids itching)

What are the existing conditions these people have? *

Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 33 people, 44.00%
Psoriasis (immune-mediated disease that affects the skin): 16 people, 21.33%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 6.67%
Pemphigoid (tense blisters on the skin): 4 people, 5.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 5.33%
Iridocyclitis (inflammation of the iris and ciliary body of the eye): 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

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