Hydrocortisone and Sensipar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocortisone (hydrocortisone) and Sensipar (cinacalcet hydrochloride). Common drug interactions include nephrogenic systemic fibrosis among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocortisone and Sensipar. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Sensipar?

Sensipar has active ingredients of cinacalcet hydrochloride. It is often used in hyperparathyroidism secondary. eHealthMe is studying from 46,034 Sensipar users. Check the latest studies of Sensipar.



On Aug, 11, 2026

34 people who take Hydrocortisone and Sensipar together, and have interactions are studied.

Hydrocortisone and Sensipar drug interactions.

What are the common drug interactions of Hydrocortisone and Sensipar, by gender? *:

female:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  3. Oedema peripheral (superficial swelling)
  4. Skin hyperpigmentation (disorders affect the colour of your skin)
  5. Skin hypertrophy (skin cells enlarges)
  6. Skin induration (an abnormally hard spot or area on the skin)
  7. Skin plaque (red, scaly patches to appear on the skin)
  8. Skin tightness
  9. Abasia (inability to walk)
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable)

male:

  1. Pain
  2. Renal failure (kidney dysfunction)
  3. Fatigue (feeling of tiredness)
  4. Joint lock
  5. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  6. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  7. Peroneal nerve palsy
  8. Vascular calcification (deposits of calcium in the blood vessels)
  9. Anaemia (lack of blood)
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the common drug interactions of Hydrocortisone and Sensipar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Arthralgia (joint pain)
  2. Back pain
  3. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  4. Fall
  5. Joint lock
  6. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  7. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  8. Pain
  9. Peroneal nerve palsy
  10. Vascular calcification (deposits of calcium in the blood vessels)

30-39:

n/a

40-49:

  1. Asthenia (weakness)
  2. Anaemia (lack of blood)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Blood creatinine increased
  6. Chronic kidney disease
  7. Emotional distress
  8. Fatigue (feeling of tiredness)
  9. Foot fracture
  10. Mobility decreased (ability to move is reduced)

50-59:

  1. Deformity (disfigurement)
  2. Erythema (redness of the skin)
  3. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  4. General physical health deterioration (weak health status)
  5. Joint range of motion decreased (disease of joint movement)
  6. Joint stiffness
  7. Mobility decreased (ability to move is reduced)
  8. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  9. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  10. Oedema peripheral (superficial swelling)

60+:

  1. Anxiety
  2. Anaemia (lack of blood)
  3. Cardioactive drug level increased
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Diarrhoea
  6. Hypertension (high blood pressure)
  7. Hypophagia (reduced food intake)
  8. Impaired healing
  9. Unresponsive to stimuli
  10. Abdominal distension

What are the existing conditions these people have? *

  1. Pain: 3 people, 8.82%
  2. Nuclear Magnetic Resonance Imaging Brain: 3 people, 8.82%
  3. Hiv Infection: 3 people, 8.82%
  4. High Blood Pressure: 3 people, 8.82%
  5. Back Pain: 3 people, 8.82%
  6. Adrenal Disorder: 3 people, 8.82%
  7. Tumor: 2 people, 5.88%
  8. Thyroid Cancer: 2 people, 5.88%
  9. Oedema Peripheral (superficial swelling): 2 people, 5.88%
  10. Joint Swelling: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and Sensipar?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydrocortisone and Sensipar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sensipar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocortisone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sensipar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone and cinacalcet hydrochloride (the active ingredients of Hydrocortisone and Sensipar, respectively), and Hydrocortisone and Sensipar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe:

No recent updates.