Hydrocortisone and Vasotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocortisone (hydrocortisone) and Vasotec (enalapril maleate). Common drug interactions include abscess among females and cardiomegaly among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocortisone and Vasotec. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

On Jul, 14, 2026

73 people who take Hydrocortisone and Vasotec together, and have interactions are studied.

Hydrocortisone and Vasotec drug interactions.

What are the common drug interactions of Hydrocortisone and Vasotec, by gender? *:

female:

Abscess (pus)
Bone disorder
Carotid bruit (sound heard over the carotid artery area during auscultation)
Cellulitis (infection under the skin)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fatigue (feeling of tiredness)
Fistula (an abnormal connection or passageway between two)
Gingival erosion (gum ulcer)
Hypophagia (reduced food intake)
Jaw disorder (jaw disease)

male:

Cardiomegaly (increased size of heart than normal)
Pain in jaw
Haemorrhage (bleeding)
Hot flush (sudden feelings of heat)
Infection
Injury
Loose tooth
Lymphadenopathy (disease or enlargement of lymph nodes)
Metastases to lymph nodes (cancer spreads to lymph node)
Metastases to reproductive organ (cancer spreads to reproductive organ)

What are the common drug interactions of Hydrocortisone and Vasotec, by age (0-1 to 60+)? *:

0-1:

Arrhythmia (irregular heartbeat)
Cardiac failure
Dyspnoea (difficult or laboured respiration)
Hepatic failure (liver failure)
Hyperhidrosis (abnormally increased sweating)
Hypotension (abnormally low blood pressure)
Organ failure
Sepsis (a severe blood infection that can lead to organ failure and death)
Urticaria (rash of round, red welts on the skin that itch intensely)

2-9:

n/a

10-19:

Bezoar (mass found trapped in the gastrointestinal system)
Gastrointestinal obstruction
Intestinal obstruction
Vomiting

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Asthenia (weakness)
Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Mobility decreased (ability to move is reduced)
Muscle tightness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

30-39:

Deformity (disfigurement)
Erythema (redness of the skin)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Rash
Rash papular (redness with papule)
Scar
Septic shock (shock due to blood infection)
Skin atrophy (wasting of skin)
Skin exfoliation (removal of the oldest dead skin cells)

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus
Cardiac disorder
Circulatory collapse
Death
Sick sinus syndrome (a collection of heart rhythm disorders)
Arthropathy
Neuropathy peripheral (surface nerve damage)
Abdominal distension
Alopecia (absence of hair from areas of the body)

50-59:

Aspartate aminotransferase increased
Asthenia (weakness)
Ataxia (loss of full control of bodily movements)
Blood alkaline phosphatase increased
Blood creatine phosphokinase increased
Blood pressure decreased
Choreoathetosis (involuntary movement randomly from one part to another body part)
Dehydration (dryness resulting from the removal of water)
Dizziness
Hyperhidrosis (abnormally increased sweating)

60+:

Weight decreased
Anaemia (lack of blood)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Cardiomegaly (increased size of heart than normal)
Gynaecomastia (enlargement of the gland tissue of the male breast)
Haemorrhage (bleeding)
Hot flush (sudden feelings of heat)
Infection
Injury
Loose tooth

What are the existing conditions these people have? *

Prostate Cancer: 14 people, 19.18%
Stress And Anxiety: 12 people, 16.44%
Depression: 8 people, 10.96%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 8.22%
Bladder Disorder: 6 people, 8.22%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 6 people, 8.22%
Fluid Overload (too much fluid in the blood): 6 people, 8.22%
Fungal Infection: 6 people, 8.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.22%
Abdominal Discomfort: 6 people, 8.22%

* Approximation only. Some reports may have incomplete information.

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