Hydrodiuril and Vibramycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrodiuril (hydrochlorothiazide) and Vibramycin (doxycycline). Common drug interactions include anxiety among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrodiuril and Vibramycin. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrodiuril?

Hydrodiuril has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,211 Hydrodiuril users. Check the latest studies of Hydrodiuril.

What is Vibramycin?

Vibramycin has active ingredients of doxycycline. It is often used in acne. eHealthMe is studying from 1,692 Vibramycin users. Check the latest studies of Vibramycin.

On Jul, 15, 2026

18 people who take Hydrodiuril and Vibramycin together, and have interactions are studied.

Hydrodiuril and Vibramycin drug interactions.

What are the common drug interactions of Hydrodiuril and Vibramycin, by gender? *:

female:

Anxiety
Pain
Arteriosclerosis (thickening and hardening of arteries)
Back pain
Blood glucose increased
Cardiovascular disorder (heart diseases)
Cataract (clouding of the lens inside the eye)
Drug ineffective
Glycosylated haemoglobin increased
Hypoaesthesia (reduced sense of touch or sensation)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Nodule (a growth of abnormal tissue)
Oedema (fluid collection in tissue)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Respiratory failure (inadequate gas exchange by the respiratory system)
Road traffic accident
Skin infection
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the common drug interactions of Hydrodiuril and Vibramycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

40-49:

Anxiety
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dyspnoea (difficult or laboured respiration)
Pain
Pneumonia
Swelling

50-59:

Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Follicular thyroid cancer (cancer of the thyroid)
Papillary thyroid cancer
Thyroid cancer

60+:

Renal failure (kidney dysfunction)
Anxiety
Insomnia (sleeplessness)
Mobility decreased (ability to move is reduced)
Muscle tightness
Peripheral swelling
Tremor (trembling or shaking movements in one or more parts of your body)
Weight increased
Pain
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 50.00%
Rosacea (a skin condition that causes facial redness): 8 people, 44.44%
Wheezing (a high-pitched whistling sound made while you breath): 7 people, 38.89%
Pain: 7 people, 38.89%
Diabetes: 6 people, 33.33%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 27.78%
Gout (uric acid crystals building up in the body): 5 people, 27.78%
Neuropathy Peripheral (surface nerve damage): 5 people, 27.78%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 5 people, 27.78%
Thyroid Diseases: 5 people, 27.78%

* Approximation only. Some reports may have incomplete information.

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