Hydroxyurea and Aricept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Aricept (donepezil hydrochloride). Common drug interactions include pancreatitis among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Aricept. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.



On Jul, 10, 2026

32 people who take Hydroxyurea and Aricept together, and have interactions are studied.

Hydroxyurea and Aricept drug interactions.

What are the common drug interactions of Hydroxyurea and Aricept, by gender? *:

female:

  1. Pancreatitis (inflammation of pancreas)
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Ileus (a painful obstruction of the ileum or other part of the intestine)
  4. Pancreatic necrosis (death of pancreas tissue in pancreas)
  5. Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
  6. Pancreatic pseudocyst (collection of tissue and fluids that forms on pancreas)
  7. Pneumonia
  8. Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
  9. Wound infection
  10. Back pain

male:

  1. Anaemia (lack of blood)
  2. Muscle haemorrhage (bleeding in muscle)
  3. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  4. Muscle cramps (painful sensations caused by muscle contraction)
  5. Cough
  6. Gastric ulcer (stomach ulcer)
  7. Gastric ulcer haemorrhage (bleeding ulcer of stomach)
  8. Haematemesis (vomiting of blood)
  9. Infection
  10. Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)

What are the common drug interactions of Hydroxyurea and Aricept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)

60+:

  1. Pancreatitis (inflammation of pancreas)
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Small intestinal obstruction (blockage in small intestine)
  4. Anaemia (lack of blood)
  5. Ascites (accumulation of fluid in the abdominal cavity)
  6. Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
  7. Colonic obstruction (obstruction in colon)
  8. Eructation (release of gas from the digestive tract)
  9. Haemoglobin decreased
  10. Muscle haemorrhage (bleeding in muscle)

What are the existing conditions these people have? *

  1. Primary Myelofibrosis (primary disorder of the bone marrow): 8 people, 25.00%
  2. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 7 people, 21.88%
  3. Thrombocytosis: 3 people, 9.38%
  4. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 9.38%
  5. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and Aricept?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydroxyurea and Aricept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aricept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyurea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aricept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea and donepezil hydrochloride (the active ingredients of Hydroxyurea and Aricept, respectively), and Hydroxyurea and Aricept (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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