Hydroxyurea and Carboplatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Carboplatin (carboplatin). Common drug interactions include anaemia among females and pancytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Carboplatin. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Carboplatin?

Carboplatin has active ingredients of carboplatin. It is often used in cancer. eHealthMe is studying from 128,210 Carboplatin users. Check the latest studies of Carboplatin.

On Aug, 13, 2026

31 people who take Hydroxyurea and Carboplatin together, and have interactions are studied.

Hydroxyurea and Carboplatin drug interactions.

What are the common drug interactions of Hydroxyurea and Carboplatin, by gender? *:

female:

Anaemia (lack of blood)
Fatigue (feeling of tiredness)
Leukopenia (less number of white blood cells in blood)
Malignant neoplasm progression (cancer tumour came back)
Metastases to bone (cancer spreads to bone)
Metastases to liver (cancer spreads to liver)
Metastases to lung (cancer spreads to lung)
Skin toxicity (skin damage due to toxin/poison)
Thrombocytopenia (decrease of platelets in blood)
Thrombosis (formation of a blood clot inside a blood vessel)

male:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Anaemia (lack of blood)
Metastases to skin (cancer spreads to skin)
Myelosuppression (a decrease in the production of blood cells)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Recurrent cancer (repeated cancer)
Renal failure (kidney dysfunction)
Skin flap necrosis (damage of flat thin layer of skin)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)

What are the common drug interactions of Hydroxyurea and Carboplatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Drug ineffective

20-29:

Hemiparesis (weakness on one side of the body)
Malignant neoplasm progression (cancer tumour came back)
Metastases to skin (cancer spreads to skin)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Recurrent cancer (repeated cancer)
Skin flap necrosis (damage of flat thin layer of skin)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Anaemia (lack of blood)

30-39:

Blood beta-d-glucan increased
Febrile neutropenia (fever with reduced white blood cells)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hemorrhagic tumour necrosis (death of body tissue with bleeding tumour)
Malignant fibrous histiocytoma (a cancer tumour of uncertain origin that arises both in soft tissue and bone)
Metastases to lung (cancer spreads to lung)
Pneumonia
Respiratory failure (excl neonatal) (inadequate gas exchange by the respiratory system(excluding neonatal))
White blood cell count decreased

40-49:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Renal failure (kidney dysfunction)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Anaemia (lack of blood)
Anal fistula
Arthralgia (joint pain)
Asthenia (weakness)
Band neutrophil percentage decreased
Basophil count increased
Basophil percentage increased

50-59:

Failure to thrive (inadequate weight gain and physical growth in children)
Dehydration (dryness resulting from the removal of water)
Dysphagia (a condition in which swallowing is difficult or painful)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Intestinal obstruction
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Transaminases increased

60+:

Leukopenia (less number of white blood cells in blood)
Anaemia (lack of blood)
Mucosal inflammation (infection of mucous membrane)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Sepsis (a severe blood infection that can lead to organ failure and death)
General physical condition
General physical health deterioration (weak health status)
Metastases to peritoneum (cancer spreads to peritoneum)
Myelosuppression (a decrease in the production of blood cells)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)

What are the existing conditions these people have? *

Oral Cancer (mouth cancer): 7 people, 22.58%
Malignant Melanoma (skin cancer rises from melancytes): 3 people, 9.68%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 9.68%
Pneumonia: 2 people, 6.45%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 6.45%
Leiomyosarcoma (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue): 2 people, 6.45%
Ependymoma Malignant (cancer in the brain): 2 people, 6.45%
Chronic Myelomonocytic Leukaemia (cancers of the blood-forming cells of the bone marrow): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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