Hydroxyurea and Cialis drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Cialis (tadalafil). Common drug interactions include chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Cialis. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Hydroxyurea?
Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.
What is Cialis?
Cialis has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 28,532 Cialis users. Check the latest studies of Cialis.
21 people who take Hydroxyurea and Cialis together, and have interactions are studied.

What are the common drug interactions of Hydroxyurea and Cialis, by gender? *:
female:
n/a
male:
- Chronic kidney disease
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Cough
- Drooling (drop saliva uncontrollably from the mouth)
- Drug hypersensitivity
- Fatigue (feeling of tiredness)
- Gout (uric acid crystals building up in the body)
- Multiple allergies (allergy to multiple agents)
- Nausea (feeling of having an urge to vomit)
- Oedema peripheral (superficial swelling)
What are the common drug interactions of Hydroxyurea and Cialis, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Asthenia (weakness)
- Nausea (feeling of having an urge to vomit)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Rash
- Red blood cell count decreased
- Tremor (trembling or shaking movements in one or more parts of your body)
- Vomiting
40-49:
n/a
50-59:
- Chronic kidney disease
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
60+:
- Dizziness
- Anisocytosis (patient's red blood cells are of unequal size)
- Blood bilirubin increased
- Cough
- Death
- Drooling (drop saliva uncontrollably from the mouth)
- Drug hypersensitivity
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
- Platelet count decreased
- Red blood cell count decreased
What are the existing conditions these people have? *
- High Blood Pressure: 4 people, 19.05%
- Infection: 4 people, 19.05%
- Cough: 4 people, 19.05%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 19.05%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 19.05%
- High Blood Cholesterol: 4 people, 19.05%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 19.05%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 19.05%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 19.05%
- Pain: 4 people, 19.05%
* Approximation only. Some reports may have incomplete information.
Do you take Hydroxyurea and Cialis?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Hydroxyurea (17,240 reports)
- Cialis (28,532 reports)
Browse all drug interactions of Hydroxyurea and Cialis:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydroxyurea:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cialis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyurea and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cialis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydroxyurea and tadalafil (the active ingredients of Hydroxyurea and Cialis, respectively), and Hydroxyurea and Cialis (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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