Hydroxyurea and Epipen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Epipen (epinephrine). Common drug interactions include diarrhoea among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Epipen. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Epipen?

Epipen has active ingredients of epinephrine. It is often used in anaphylaxis. eHealthMe is studying from 23,760 Epipen users. Check the latest studies of Epipen.

On Jul, 05, 2026

28 people who take Hydroxyurea and Epipen together, and have interactions are studied.

Hydroxyurea and Epipen drug interactions.

What are the common drug interactions of Hydroxyurea and Epipen, by gender? *:

female:

Diarrhoea
Flushing (the warm, red condition of human skin)
Haemoglobin decreased
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Pneumonia
Pruritus generalised (generalized itching)
Pyrexia (fever)
Therapeutic response decreased (less preventive response)
Throat irritation

male:

Arthralgia (joint pain)
Blood phosphorus decreased
Groin pain
Nasopharyngitis (inflammation of the nasopharynx)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Pain
Pain in extremity
Fatigue (feeling of tiredness)
Gastric disorder (disease of stomach)
Headache (pain in head)

What are the common drug interactions of Hydroxyurea and Epipen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Haemoglobin decreased
Nasopharyngitis (inflammation of the nasopharynx)
Pyrexia (fever)

20-29:

n/a

30-39:

Blood phosphorus decreased
Acne (skin problems that cause pimples)
Arthralgia (joint pain)
Dry skin
Electrocardiogram qt prolonged
Haemoglobin decreased
Hepatic enzyme increased
White blood cell count decreased
Blood sodium decreased
Groin pain

40-49:

Diarrhoea
Flushing (the warm, red condition of human skin)
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Pruritus generalised (generalized itching)
Therapeutic response decreased (less preventive response)
Throat irritation

50-59:

n/a

60+:

Death
Tooth abscess (pus formation in tooth)
Toothache (tooth pain)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 13 people, 46.43%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 8 people, 28.57%
Immunodeficiency Common Variable: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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