Hydroxyurea and Everolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Everolimus (everolimus). Common drug interactions include hepatosplenic candidiasis among females and blood sodium decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Everolimus. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Everolimus?

Everolimus has active ingredients of everolimus. eHealthMe is studying from 16,228 Everolimus users. Check the latest studies of Everolimus.



On Jul, 21, 2026

11 people who take Hydroxyurea and Everolimus together, and have interactions are studied.

Hydroxyurea and Everolimus drug interactions.

What are the common drug interactions of Hydroxyurea and Everolimus, by gender? *:

female:

  1. Hepatosplenic candidiasis (fungal infection in liver and spleen)
  2. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  3. Pericarditis (inflammation of the pericardium)
  4. Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
  5. Septic shock (shock due to blood infection)
  6. Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
  7. Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
  8. Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
  9. Neoplasm progression (growth of tumour)
  10. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)

male:

  1. Blood sodium decreased
  2. Cellulitis (infection under the skin)
  3. Loss of consciousness
  4. Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
  5. Pneumonia
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Drug ineffective

What are the common drug interactions of Hydroxyurea and Everolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  2. Cellulitis (infection under the skin)
  3. Hepatosplenic candidiasis (fungal infection in liver and spleen)
  4. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  5. Pericarditis (inflammation of the pericardium)
  6. Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
  7. Septic shock (shock due to blood infection)
  8. Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
  9. Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
  10. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)

30-39:

n/a

40-49:

  1. Blood sodium decreased
  2. Cellulitis (infection under the skin)
  3. Loss of consciousness
  4. Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
  5. Pneumonia
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
  8. Neoplasm progression (growth of tumour)

50-59:

n/a

60+:

  1. Drug ineffective

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 63.64%
  2. Bone Marrow Conditioning Regimen: 6 people, 54.55%
  3. Neoplasm Malignant (cancer tumour): 1 person, 9.09%
  4. Meningioma (a diverse set of tumours arising from the meninges): 1 person, 9.09%
  5. Brain Neoplasm Malignant (brain cancer tumour): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and Everolimus?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydroxyurea and Everolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Everolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyurea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Everolimus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea and everolimus (the active ingredients of Hydroxyurea and Everolimus, respectively), and Hydroxyurea and Everolimus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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