Hydroxyurea and Lotemax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Lotemax (loteprednol etabonate). Common drug interactions include asthenia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Lotemax. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Lotemax?

Lotemax has active ingredients of loteprednol etabonate. It is often used in inflammation. eHealthMe is studying from 4,431 Lotemax users. Check the latest studies of Lotemax.

On Jul, 12, 2026

16 people who take Hydroxyurea and Lotemax together, and have interactions are studied.

Hydroxyurea and Lotemax drug interactions.

What are the common drug interactions of Hydroxyurea and Lotemax, by gender? *:

female:

Asthenia (weakness)
Nausea (feeling of having an urge to vomit)
Vomiting
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Syncope vasovagal (malfunction in the parts of the nervous system leads to consciousness with an inability to maintain postural tone)
Oral disorder (mouth disease)
Blood creatinine increased
Constipation
Diarrhoea
Electrocardiogram qt prolonged

male:

Diarrhoea
Infection
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Bone pain
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Muscular weakness (muscle weakness)
Tooth fracture
Tooth loss

What are the common drug interactions of Hydroxyurea and Lotemax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Asthenia (weakness)
Nausea (feeling of having an urge to vomit)
Electrocardiogram qt prolonged
Eye disorder
Fatigue (feeling of tiredness)
Furuncle (infection of the hair follicle)
Headache (pain in head)
Hyperglycaemia (high blood sugar)
Hypoaesthesia (reduced sense of touch or sensation)
Hypophagia (reduced food intake)

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 7 people, 43.75%
Rosacea (a skin condition that causes facial redness): 5 people, 31.25%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 31.25%
High Blood Pressure: 5 people, 31.25%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 25.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 25.00%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 1 person, 6.25%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 1 person, 6.25%
Hyperkalemia (damage to or disease of the kidney): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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