Hydroxyurea and Pentoxifylline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Pentoxifylline (pentoxifylline). Common drug interactions include fall among females and glaucoma among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Pentoxifylline. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Pentoxifylline?

Pentoxifylline has active ingredients of pentoxifylline. eHealthMe is studying from 5,997 Pentoxifylline users. Check the latest studies of Pentoxifylline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

19 people who take Hydroxyurea and Pentoxifylline together, and have interactions are studied.

Hydroxyurea and Pentoxifylline drug interactions.

What are the common drug interactions of Hydroxyurea and Pentoxifylline, by gender? *:

female:

Fall
Injection site reaction
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Balance disorder
Carotid arteriosclerosis (plaque deposition in artery)
Clumsiness (a lack of coordination or elegance)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Compression fracture (fracture due to pressure caused by injury)

male:

Glaucoma (increased fluid pressure in the eye with vision loss)
Muscle spasms (muscle contraction)
Death
Hypoxia (low oxygen in tissues)
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)
Platelet count increased
Pyrexia (fever)
Respiratory distress (difficulty in breathing)

What are the common drug interactions of Hydroxyurea and Pentoxifylline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Bacteria stool identified
Clostridial infection (infectious conditions by clostridium bacteria)
Hypoxia (low oxygen in tissues)
Pyrexia (fever)
Respiratory distress (difficulty in breathing)

60+:

Anaemia (lack of blood)
Glaucoma (increased fluid pressure in the eye with vision loss)
Asthenia (weakness)
Balance disorder
Blood potassium increased
Clumsiness (a lack of coordination or elegance)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Compression fracture (fracture due to pressure caused by injury)
Confusional state
Death

What are the existing conditions these people have? *

Peripheral Arterial Occlusive Disease (reproducible ischemic muscle pain): 7 people, 36.84%
High Blood Pressure: 6 people, 31.58%
Hyperkalemia (damage to or disease of the kidney): 4 people, 21.05%
Primary Myelofibrosis (primary disorder of the bone marrow): 4 people, 21.05%
Insomnia (sleeplessness): 4 people, 21.05%
Hypertensive Heart Disease: 3 people, 15.79%
Constipation: 3 people, 15.79%
Chronic Kidney Disease: 3 people, 15.79%
Allergies: 3 people, 15.79%
Diabetes: 3 people, 15.79%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and Pentoxifylline?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously