Hydroxyurea and Prinivil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Prinivil (lisinopril). Common drug interactions include respiratory acidosis among females and acute chest syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Prinivil. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.

On Jul, 10, 2026

23 people who take Hydroxyurea and Prinivil together, and have interactions are studied.

Hydroxyurea and Prinivil drug interactions.

What are the common drug interactions of Hydroxyurea and Prinivil, by gender? *:

female:

Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
Reticulocyte count increased
Rhinorrhoea (watery mucus discharge from the nose)
Somnolence (a state of near-sleep, a strong desire for sleep)
Surgery
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bradycardia (abnormally slow heart action)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

male:

Acute chest syndrome (acute chest pain, fever and difficulty breathing)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Diarrhoea
Disturbance in attention
Dizziness
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea exertional (breathlessness or shortness of breath)
Erythema multiforme (a type of hypersensitivity reaction)
Fatigue (feeling of tiredness)

What are the common drug interactions of Hydroxyurea and Prinivil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Acute chest syndrome (acute chest pain, fever and difficulty breathing)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

30-39:

n/a

40-49:

n/a

50-59:

Bronchial hyperreactivity
Chills (felling of cold)
Cough
Hypercapnia (too much smoke)
Neck pain
Oropharyngeal pain
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Eye swelling
Fluid overload (too much fluid in the blood)
Head banging (violently shaking the head in time with the music)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Injury
Multiple injuries
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

What are the existing conditions these people have? *

Platelet Count Increased: 3 people, 13.04%
Nausea (feeling of having an urge to vomit): 3 people, 13.04%
Blood Uric Acid Increased: 3 people, 13.04%
Stress And Anxiety: 2 people, 8.70%
Pain: 2 people, 8.70%
Itching: 2 people, 8.70%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 8.70%
Constipation: 2 people, 8.70%
Asplenia (absence of normal spleen function and is associated with some serious infection risks): 2 people, 8.70%
Acne (skin problems that cause pimples): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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