Hydroxyzine hydrochloride and Avapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine hydrochloride (hydroxyzine hydrochloride) and Avapro (irbesartan). Common drug interactions include fatigue among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine hydrochloride and Avapro. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine hydrochloride?

Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 10,486 Hydroxyzine hydrochloride users. Check the latest studies of Hydroxyzine hydrochloride.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

15 people who take Hydroxyzine hydrochloride and Avapro together, and have interactions are studied.

Hydroxyzine hydrochloride and Avapro drug interactions.

What are the common drug interactions of Hydroxyzine Hydrochloride and Avapro, by gender? *:

female:

Fatigue (feeling of tiredness)
Blood immunoglobulin g increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac valve disease (heart valve disease)
Electrolyte imbalance
Fall
Headache (pain in head)
Infusion related reaction
Mitral valve prolapse (heart's mitral valve doesn't work well)
Pelvic fracture

male:

Chronic kidney disease
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dyslipidaemia (abnormal amount of lipids)
Dyspepsia (indigestion)
Gout (uric acid crystals building up in the body)
Hypoaesthesia (reduced sense of touch or sensation)
Hypokalaemia (low potassium)

What are the common drug interactions of Hydroxyzine Hydrochloride and Avapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dyspepsia (indigestion)
Renal cyst (kidney cyst)
Renal failure (kidney dysfunction)
Abdominal discomfort
Abdominal pain
Angina pectoris (chest pain due to ischemia of the heart muscle)
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Benign prostatic hyperplasia (benign enlargement of the prostate)

60+:

Biliary cirrhosis primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver)
Chronic kidney disease
Stomatitis (inflammation of mucous membrane of mouth)
Weight decreased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Dumping syndrome (a condition that can develop after surgery to remove all or part of your stomach or after surgery to bypass your stomach to help you lose weight)
Eating disorder
Fatigue (feeling of tiredness)
Irritable bowel syndrome

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 20.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 20.00%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 13.33%
Asthma: 2 people, 13.33%
Osteoporosis (bones weak and more likely to break): 2 people, 13.33%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 2 people, 13.33%
Itching: 2 people, 13.33%
Irritable Bowel Syndrome: 2 people, 13.33%
Immunodeficiency Common Variable: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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