Hydroxyzine hydrochloride and Indapamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine hydrochloride (hydroxyzine hydrochloride) and Indapamide (indapamide). Common drug interactions include pain among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine hydrochloride and Indapamide. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine hydrochloride?

Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 10,486 Hydroxyzine hydrochloride users. Check the latest studies of Hydroxyzine hydrochloride.

What is Indapamide?

Indapamide has active ingredients of indapamide. It is often used in high blood pressure. eHealthMe is studying from 22,153 Indapamide users. Check the latest studies of Indapamide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

18 people who take Hydroxyzine hydrochloride and Indapamide together, and have interactions are studied.

Hydroxyzine hydrochloride and Indapamide drug interactions.

What are the common drug interactions of Hydroxyzine Hydrochloride and Indapamide, by gender? *:

female:

Pain
Drug ineffective
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Depression
Acute myocardial infarction (acute heart attack)

male:

Chronic kidney disease
Hypercreatininaemia (high levels of creatine in the blood)
Nephropathy (damage to or disease of a kidney)
Renal failure (kidney dysfunction)

What are the common drug interactions of Hydroxyzine Hydrochloride and Indapamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Burning mouth syndrome (pain in the mouth and burning sensation on tongue)
Back pain
Dysphagia (a condition in which swallowing is difficult or painful)
Hypophagia (reduced food intake)
Iron deficiency
Oral discomfort (pain or irritation in mouth)
Pain
Drug ineffective
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

60+:

Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Septic shock (shock due to blood infection)
Vomiting
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Face oedema (swelling of face)
Faeces discoloured

What are the existing conditions these people have? *

Depression: 8 people, 44.44%
Insomnia (sleeplessness): 6 people, 33.33%
Spinal Pain (pain in spine): 5 people, 27.78%
Pain: 5 people, 27.78%
Diabetes: 3 people, 16.67%
High Blood Cholesterol: 3 people, 16.67%
Initial Insomnia (feeling of inadequate or poor-quality sleep): 3 people, 16.67%
Back Pain: 3 people, 16.67%
Urinary Tract Infection: 2 people, 11.11%
General Physical Health Deterioration (weak health status): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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