Hydroxyzine pamoate and Actos drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine pamoate (hydroxyzine pamoate) and Actos (pioglitazone hydrochloride). Common drug interactions include renal failure among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine pamoate and Actos. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine pamoate?

Hydroxyzine pamoate has active ingredients of hydroxyzine pamoate. It is often used in stress and anxiety. eHealthMe is studying from 4,252 Hydroxyzine pamoate users. Check the latest studies of Hydroxyzine pamoate.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

On Jul, 09, 2026

18 people who take Hydroxyzine pamoate and Actos together, and have interactions are studied.

Hydroxyzine pamoate and Actos drug interactions.

What are the common drug interactions of Hydroxyzine Pamoate and Actos, by gender? *:

female:

Renal failure (kidney dysfunction)
Chronic kidney disease
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Fibromyalgia (a long-term condition which causes pain all over the body)
Mania (a state of abnormally elevated or irritable mood)
Neuropathy peripheral (surface nerve damage)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

male:

Asthenia (weakness)
Chronic kidney disease
Pancreatitis (inflammation of pancreas)
Renal failure acute (rapid kidney dysfunction)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bladder cancer
Hypertriglyceridaemia (excess of triglycerides in the blood)
Micturition urgency (urgency to pass the urine)
Disturbance in attention
Fatigue (feeling of tiredness)

What are the common drug interactions of Hydroxyzine Pamoate and Actos, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Fibromyalgia (a long-term condition which causes pain all over the body)
Mania (a state of abnormally elevated or irritable mood)
Neuropathy peripheral (surface nerve damage)
Renal failure (kidney dysfunction)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Chronic kidney disease

40-49:

Chronic kidney disease
Asthenia (weakness)
Disturbance in attention
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Joint swelling
Nocturia (the need to get up in the night to urinate)
Peripheral swelling
Renal impairment (severely reduced kidney function)
Renal failure (kidney dysfunction)

50-59:

Arthralgia (joint pain)
Back pain
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Rash
Urinary tract infection
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death
Pneumonia
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

High Blood Pressure: 11 people, 61.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 55.56%
Itching: 7 people, 38.89%
High Blood Cholesterol: 6 people, 33.33%
Depression: 6 people, 33.33%
Insomnia (sleeplessness): 5 people, 27.78%
Pain: 5 people, 27.78%
Type 2 Diabetes: 4 people, 22.22%
Infection: 4 people, 22.22%
Inflammation: 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

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