Hydroxyzine pamoate and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine pamoate (hydroxyzine pamoate) and Colace (docusate ). Common drug interactions include cardiac disorder among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine pamoate and Colace. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine pamoate?

Hydroxyzine pamoate has active ingredients of hydroxyzine pamoate. It is often used in stress and anxiety. eHealthMe is studying from 4,252 Hydroxyzine pamoate users. Check the latest studies of Hydroxyzine pamoate.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

47 people who take Hydroxyzine pamoate and Colace together, and have interactions are studied.

Hydroxyzine pamoate and Colace drug interactions.

What are the common drug interactions of Hydroxyzine Pamoate and Colace, by gender? *:

female:

Cardiac disorder
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Immune system disorder
Infection
Infusion site discomfort
Infusion site swelling
Loss of consciousness
Pneumonia bacterial (pneumonia associated with bacterial infection)
Pyrexia (fever)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

male:

Abdominal discomfort
Abdominal pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chills (felling of cold)
Chronic kidney disease
Confusional state
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death
Decreased appetite
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Hydroxyzine Pamoate and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Hyperglycaemia (high blood sugar)
Obesity (having too much body fat)
Pain
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Type 1 diabetes mellitus
Type 2 diabetes mellitus

30-39:

Arthralgia (joint pain)
Depression
Fracture
Gait disturbance
Hip fracture
Osteoporosis (bones weak and more likely to break)
Pain
Road traffic accident
Spinal fracture (fracture in one of vertebrae)
Bone density decreased

40-49:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Pyelonephritis (inflammation of kidney caused by bacteria)
Insomnia (sleeplessness)
Hunger
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Self-injurious ideation
Suicide attempt
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)

50-59:

Erythema (redness of the skin)
Muscular weakness (muscle weakness)
Neutropenia (an abnormally low number of neutrophils)
Open wound
Plasma cell myeloma (cancer that begins in plasma cells)
Pyelonephritis (inflammation of kidney caused by bacteria)
Respiratory failure (inadequate gas exchange by the respiratory system)
Scleroderma (hard skin)
White blood cell count decreased
Wound infection

60+:

Fall
Arthralgia (joint pain)
Immune system disorder
Infection
Infusion site discomfort
Infusion site swelling
Pain
Pneumonia bacterial (pneumonia associated with bacterial infection)
Pyrexia (fever)
Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 11 people, 23.40%
Hypergammaglobulinaemia (elevated levels of gamma globulin): 9 people, 19.15%
Pain: 9 people, 19.15%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 14.89%
Insomnia (sleeplessness): 7 people, 14.89%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 12.77%
Urinary Tract Infection: 5 people, 10.64%
Asthma: 5 people, 10.64%
High Blood Pressure: 5 people, 10.64%
Back Pain: 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

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