Hydroxyzine and Alrex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine (hydroxyzine hydrochloride) and Alrex (loteprednol etabonate). Common drug interactions include ocular hyperaemia among females and benign prostatic hyperplasia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Alrex. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Alrex?

Alrex has active ingredients of loteprednol etabonate. eHealthMe is studying from 663 Alrex users. Check the latest studies of Alrex.

On Jul, 04, 2026

13 people who take Hydroxyzine and Alrex together, and have interactions are studied.

Hydroxyzine and Alrex drug interactions.

What are the common drug interactions of Hydroxyzine and Alrex, by gender? *:

female:

Ocular hyperaemia (an abnormally large amount of blood in eye)
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer)
Discomfort
Endophthalmitis (inflammation of the internal coats of the eye)
Erythema (redness of the skin)
Eye infection
Pain
Chronic kidney disease
Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
Fatigue (feeling of tiredness)

male:

Benign prostatic hyperplasia (benign enlargement of the prostate)
Hypertension (high blood pressure)
Obesity (having too much body fat)
Therapeutic response unexpected
Chronic kidney disease
Renal failure (kidney dysfunction)
Weight decreased

What are the common drug interactions of Hydroxyzine and Alrex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Benign prostatic hyperplasia (benign enlargement of the prostate)
Discomfort
Endophthalmitis (inflammation of the internal coats of the eye)
Erythema (redness of the skin)
Eye infection
Eye irritation
Hypertension (high blood pressure)
Obesity (having too much body fat)
Pain
Therapeutic response unexpected

60+:

Arthralgia (joint pain)
Eye irritation
Eye pruritus (eye itching)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Chronic kidney disease
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer)
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Viral infection

What are the existing conditions these people have? *

Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 23.08%
Seasonal Allergy (allergic condition due to certain season): 3 people, 23.08%
Depression: 3 people, 23.08%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 2 people, 15.38%
Temporomandibular Joint Syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress): 2 people, 15.38%
Migraine (headache): 2 people, 15.38%
Essential Tremor: 2 people, 15.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
Immunodeficiency Common Variable: 2 people, 15.38%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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