Hydroxyzine and Crixivan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine (hydroxyzine hydrochloride) and Crixivan (indinavir sulfate). Common drug interactions include nausea among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Crixivan. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,070 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Crixivan?

Crixivan has active ingredients of indinavir sulfate. eHealthMe is studying from 6,312 Crixivan users. Check the latest studies of Crixivan.

On Aug, 12, 2026

41 people who take Hydroxyzine and Crixivan together, and have interactions are studied.

Hydroxyzine and Crixivan drug interactions.

What are the common drug interactions of Hydroxyzine and Crixivan, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Pain
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Blood sodium decreased
Creatinine renal clearance decreased
Drug ineffective
Electrolyte imbalance
Hiv wasting syndrome (aids wasting syndrome occurs when you have aids and lose at least 10% of your body weight -- especially muscle)
Osteopenia (a condition where bone mineral density is lower than normal)
Vomiting

male:

Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Decreased activity
Impaired work ability
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephrolithiasis (calculi in the kidneys)

What are the common drug interactions of Hydroxyzine and Crixivan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abnormal behaviour
Aggression
Agitation (state of anxiety or nervous excitement)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Arthralgia (joint pain)
Blood amylase increased
Blood pressure increased
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Cough
Depression

30-39:

Blood alkaline phosphatase increased
Calculus urinary (stone in urinary system)
Dehydration (dryness resulting from the removal of water)
Dizziness
Gamma-glutamyltransferase increased
Hyperlipidaemia (presence of excess lipids in the blood)
Nausea (feeling of having an urge to vomit)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Blood sodium decreased
Creatinine renal clearance decreased

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Pain
Renal impairment (severely reduced kidney function)
Renal failure (kidney dysfunction)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Decreased activity
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Pain
Chronic kidney disease
Depression
Renal failure (kidney dysfunction)
Osteopenia (a condition where bone mineral density is lower than normal)
Bone density decreased
Decreased activity
Fatigue (feeling of tiredness)

60+:

Osteoporosis (bones weak and more likely to break)
Bone density decreased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone loss
Emotional distress
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Spinal compression fracture (fracture due to spinal compression on bone)
Gait disturbance

What are the existing conditions these people have? *

Hiv Infection: 35 people, 85.37%
Infection: 10 people, 24.39%
Hypersensitivity: 8 people, 19.51%
Cough: 8 people, 19.51%
Pain: 8 people, 19.51%
High Blood Pressure: 8 people, 19.51%
Fungal Infection: 6 people, 14.63%
Bacterial Infection: 6 people, 14.63%
Diabetes: 5 people, 12.20%
High Blood Cholesterol: 5 people, 12.20%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine and Crixivan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously