Hydroxyzine and Lac-hydrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyzine (hydroxyzine hydrochloride) and Lac-hydrin (ammonium lactate). Common drug interactions include headache among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyzine and Lac-hydrin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Lac-hydrin?

Lac-hydrin has active ingredients of ammonium lactate. eHealthMe is studying from 534 Lac-hydrin users. Check the latest studies of Lac-hydrin.



On Jul, 10, 2026

22 people who take Hydroxyzine and Lac-hydrin together, and have interactions are studied.

Hydroxyzine and Lac-hydrin drug interactions.

What are the common drug interactions of Hydroxyzine and Lac-Hydrin, by gender? *:

female:

  1. Headache (pain in head)
  2. Histoplasmosis (infection caused by breathing in spores of a fungus)
  3. Hypertension (high blood pressure)
  4. Weight increased
  5. Acute sinusitis
  6. Alopecia (absence of hair from areas of the body)
  7. Anaemia (lack of blood)
  8. Arthropathy
  9. Asthma
  10. Blood alkaline phosphatase increased

male:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  4. Balance disorder
  5. Blood acid phosphatase increased
  6. Carcinoid tumour (slow growing tumour)
  7. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  8. Chest discomfort
  9. Coronary arterial stent insertion
  10. Coronary artery stenosis (narrowing of coronary artery)

What are the common drug interactions of Hydroxyzine and Lac-Hydrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hodgkin's disease (cancer originating from white blood cells)
  2. Impetigo (contagious skin infection)
  3. Keratoconjunctivitis sicca (inflammation of the conjunctiva and cornea of the eye with decreased tears)
  4. Lacrimation increased
  5. Lung disorder (lung disease)
  6. Lymphadenopathy (disease or enlargement of lymph nodes)
  7. Neuropathy peripheral (surface nerve damage)
  8. Oral herpes (viral infection of mouth)
  9. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  10. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)

30-39:

  1. Ligament rupture (tear in ligament)
  2. Nausea (feeling of having an urge to vomit)
  3. Platelet count decreased
  4. Rash pruritic (redness with itching)

40-49:

  1. Death
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  4. Fibromyalgia (a long-term condition which causes pain all over the body)
  5. Gastrointestinal pain
  6. Hypertension (high blood pressure)
  7. Non-cardiac chest pain
  8. Pancreatitis chronic (chronic inflammation of pancreas)
  9. Polyp colorectal
  10. Suicidal behaviour

50-59:

  1. Headache (pain in head)
  2. Abdominal pain
  3. Acute sinusitis
  4. Alopecia (absence of hair from areas of the body)
  5. Anaemia (lack of blood)
  6. Arthropathy
  7. Asthma
  8. Blood alkaline phosphatase increased
  9. Blood glucose increased
  10. Breast mass

60+:

  1. Eating disorder
  2. Infection
  3. Leukopenia (less number of white blood cells in blood)
  4. Nausea (feeling of having an urge to vomit)
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  7. Vomiting
  8. Weight increased
  9. Pain
  10. Chronic kidney disease

What are the existing conditions these people have? *

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 6 people, 27.27%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 27.27%
  3. Oropharyngeal Pain: 6 people, 27.27%
  4. Wheezing (a high-pitched whistling sound made while you breath): 4 people, 18.18%
  5. Migraine (headache): 4 people, 18.18%
  6. Asthma: 4 people, 18.18%
  7. Dyspnea (difficult or laboured breathing): 4 people, 18.18%
  8. Itching: 4 people, 18.18%
  9. Hypersensitivity: 4 people, 18.18%
  10. Pain: 4 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydroxyzine and Lac-hydrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lac-hydrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyzine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lac-hydrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride and ammonium lactate (the active ingredients of Hydroxyzine and Lac-hydrin, respectively), and Hydroxyzine and Lac-hydrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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