Hygroton and Flomax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hygroton (chlorthalidone) and Flomax (tamsulosin hydrochloride). Common drug interactions include upper gastrointestinal haemorrhage among females and intraocular pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Hygroton and Flomax. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Hygroton?

Hygroton has active ingredients of chlorthalidone. It is often used in high blood pressure. eHealthMe is studying from 1,463 Hygroton users. Check the latest studies of Hygroton.

What is Flomax?

Flomax has active ingredients of tamsulosin hydrochloride. It is often used in enlarged prostate. eHealthMe is studying from 52,865 Flomax users. Check the latest studies of Flomax.

On Jul, 11, 2026

27 people who take Hygroton and Flomax together, and have interactions are studied.

What are the common drug interactions of Hygroton and Flomax, by gender? *:

female:

Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

male:

Intraocular pressure increased
Abdominal distension
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood sodium decreased
Cardiac disorder
Conjunctivitis (pink eye)
Decreased interest
Disability
Dizziness
Drug hypersensitivity

What are the common drug interactions of Hygroton and Flomax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal distension
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood sodium decreased
Conjunctivitis (pink eye)
Drug hypersensitivity
Immunoglobulins decreased
Inappropriate antidiuretic hormone secretion
Infusion related reaction
Infusion site pain
Injection site erythema (redness at injection site)

50-59:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

60+:

Intraocular pressure increased
Drug ineffective
Disease progression
Fatigue (feeling of tiredness)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic failure (liver failure)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Impaired healing
Lactic acidosis (low ph in body tissues)

What are the existing conditions these people have? *

Pain: 8 people, 29.63%
Gastric Disorder (disease of stomach): 6 people, 22.22%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 14.81%
Sleep Disorder: 4 people, 14.81%
Muscle Spasms (muscle contraction): 4 people, 14.81%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.81%
Prostatic Disorder: 3 people, 11.11%
Primary Immunodeficiency Syndrome: 3 people, 11.11%
Immunodeficiency Common Variable: 3 people, 11.11%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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