Hysingla and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hysingla (hydrocodone bitartrate) and Colace (docusate ). Common drug interactions include depression among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Hysingla and Colace. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Hysingla?

Hysingla has active ingredients of hydrocodone bitartrate. eHealthMe is studying from 32,609 Hysingla users. Check the latest studies of Hysingla.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

On Jul, 16, 2026

19 people who take Hysingla and Colace together, and have interactions are studied.

What are the common drug interactions of Hysingla and Colace, by gender? *:

female:

Depression
Drug dependence
Fall
Limb injury
Pain
Vomiting
Abdominal discomfort
Abdominal pain
Ankle fracture
Anxiety

male:

Depression
Disability
Gun shot wound
Hypertension (high blood pressure)
Injury
Memory impairment
Open fracture
Overdose
Pain
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

What are the common drug interactions of Hysingla and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal discomfort
Arthralgia (joint pain)
Chest pain
Diarrhoea
Fall
Feeding disorder (when children refuse to eat certain food groups)
Flushing (the warm, red condition of human skin)
Hand fracture
Hepatic enzyme increased
Infection

40-49:

n/a

50-59:

Face injury
Fall
Joint injury
Laceration (tearing of soft body tissue)
Limb injury
Rectal fissure (painful condition in which a cut or tear occurs in the anus)

60+:

Depression
Fatigue (feeling of tiredness)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Migraine (headache)
Small intestinal obstruction (blockage in small intestine)
Thyroid mass
Vaginal discharge
Vomiting
Abdominal pain

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 47.37%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 42.11%
Pain: 4 people, 21.05%
Drowsiness: 2 people, 10.53%
Sinusitis (inflammation of sinus): 1 person, 5.26%
Renal Cell Carcinoma (a kidney cancer): 1 person, 5.26%
Muscle Spasms (muscle contraction): 1 person, 5.26%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.26%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.26%
Insomnia (sleeplessness): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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