Hysingla and Lipitor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hysingla (hydrocodone bitartrate) and Lipitor (atorvastatin calcium). Common drug interactions include dizziness among females and blood glucose increased among males.
The phase IV clinical study analyzes what interactions people have when they take Hysingla and Lipitor. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Hysingla?
Hysingla has active ingredients of hydrocodone bitartrate. eHealthMe is studying from 32,609 Hysingla users. Check the latest studies of Hysingla.
What is Lipitor?
Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,048 Lipitor users. Check the latest studies of Lipitor.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
12 people who take Hysingla and Lipitor together, and have interactions are studied.

What are the common drug interactions of Hysingla and Lipitor, by gender? *:
female:
- Dizziness
- Drug dependence
- Dyslipidaemia (abnormal amount of lipids)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
- Overdose
- Pain
- Tobacco abuse
- Vitamin d deficiency
- Abdominal pain upper
male:
- Blood glucose increased
- Euphoric mood (excessively happy but may become angry or irritable)
- Overdose
- Rash
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Weight decreased
- White blood cell count decreased
- Fatigue (feeling of tiredness)
- Febrile neutropenia (fever with reduced white blood cells)
- Heart rate decreased
What are the common drug interactions of Hysingla and Lipitor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Arthralgia (joint pain)
- Proteinuria (presence of protein in the urine)
- Urine abnormality
50-59:
- Euphoric mood (excessively happy but may become angry or irritable)
- Heart rate decreased
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Overdose
- Somnolence (a state of near-sleep, a strong desire for sleep)
60+:
- Dizziness
- Balance disorder
- Rash
- Weight decreased
- White blood cell count decreased
- Blood glucose increased
- Ear infection
- Febrile neutropenia (fever with reduced white blood cells)
- Hypotension (abnormally low blood pressure)
- Impaired driving ability
What are the existing conditions these people have? *
- Pain: 7 people, 58.33%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 16.67%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 16.67%
- Back Pain: 2 people, 16.67%
- Dyslipidaemia (abnormal amount of lipids): 2 people, 16.67%
- Nausea And Vomiting: 2 people, 16.67%
- Nausea (feeling of having an urge to vomit): 2 people, 16.67%
- Cardiac Disorder: 1 person, 8.33%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 8.33%
- Drowsiness: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Hysingla and Lipitor?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Hysingla and Lipitor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hysingla:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lipitor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hysingla and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lipitor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on hydrocodone bitartrate and atorvastatin calcium (the active ingredients of Hysingla and Lipitor, respectively), and Hysingla and Lipitor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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