Hytrin and Apresoline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hytrin (terazosin hydrochloride) and Apresoline (hydralazine hydrochloride). Common drug interactions include disorientation among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Hytrin and Apresoline. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Hytrin?

Hytrin has active ingredients of terazosin hydrochloride. It is often used in prostate examination abnormal. eHealthMe is studying from 7,501 Hytrin users. Check the latest studies of Hytrin.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

On Jul, 25, 2026

29 people who take Hytrin and Apresoline together, and have interactions are studied.

Hytrin and Apresoline drug interactions.

What are the common drug interactions of Hytrin and Apresoline, by gender? *:

female:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Drug administration error
Dysarthria (speech disorder)
Dyspnoea exertional (breathlessness or shortness of breath)
Dysuria (painful or difficult urination)
Fall
Fatigue (feeling of tiredness)
Flat affect (absence of emotional response to a situation)
Fluid intake reduced

male:

Diarrhoea
Pain
Full blood count decreased
Neutropenia (an abnormally low number of neutrophils)
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
Fear

What are the common drug interactions of Hytrin and Apresoline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acute respiratory failure
Alanine aminotransferase increased
Aspartate aminotransferase increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Hypokalaemia (low potassium)
Laryngeal oedema (swelling of larynx)
Malignant hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Urinary tract infection

50-59:

Haemorrhagic transformation stroke (haemorrhages develop inside areas of ischemia)
Ischaemic cerebral infarction (ischemic stroke resulting from a disturbance in the blood vessels supplying blood to the brain)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Abdominal pain upper
Renal injury (kidney injury)

60+:

Diarrhoea
Pain
Full blood count decreased
Neutropenia (an abnormally low number of neutrophils)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Depression
Emotional distress
Fear

What are the existing conditions these people have? *

Pain: 7 people, 24.14%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 20.69%
Acute Kidney Failure: 4 people, 13.79%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 13.79%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 13.79%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 13.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 13.79%
Renal Cell Carcinoma (a kidney cancer): 3 people, 10.34%
Itching: 3 people, 10.34%
Nausea (feeling of having an urge to vomit): 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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