Hyzaar and Selenium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hyzaar (hydrochlorothiazide; losartan potassium) and Selenium (selenium). Common drug interactions include pruritus among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Hyzaar and Selenium. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Hyzaar?

Hyzaar has active ingredients of hydrochlorothiazide; losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 16,614 Hyzaar users. Check the latest studies of Hyzaar.

What is Selenium?

Selenium has active ingredients of selenium. It is often used in vitamin supplementation. eHealthMe is studying from 5,314 Selenium users. Check the latest studies of Selenium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

16 people who take Hyzaar and Selenium together, and have interactions are studied.

What are the common drug interactions of Hyzaar and Selenium, by gender? *:

female:

Pruritus (severe itching of the skin)
Agitation (state of anxiety or nervous excitement)
Arthralgia (joint pain)
Blood pressure systolic increased
Cold sweat
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Drug ineffective
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Feeling hot

male:

Decreased appetite
Fatigue (feeling of tiredness)
Thrombosis (formation of a blood clot inside a blood vessel)
Neutropenia (an abnormally low number of neutrophils)
Productive cough
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Spinal column stenosis (narrowing of spinal column)
Back pain
Pyrexia (fever)
Flushing (the warm, red condition of human skin)

What are the common drug interactions of Hyzaar and Selenium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Flushing (the warm, red condition of human skin)

60+:

Fatigue (feeling of tiredness)
Pruritus (severe itching of the skin)
Flushing (the warm, red condition of human skin)
H1n1 influenza (flu (influenza), which is caused by virus influenza a (h1n1))
Headache (pain in head)
Hypersensitivity
Intervertebral disc degeneration (spinal disc degeneration)
Joint swelling
Lethargy (tiredness)
Oral mucosal erythema (redness of the mucous membrane of mouth)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 50.00%
Multiple Myeloma (cancer of the plasma cells): 5 people, 31.25%
Enlarged Prostate: 5 people, 31.25%
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 4 people, 25.00%
Indigestion: 4 people, 25.00%
Back Pain: 4 people, 25.00%
Blood Creatinine Increased: 4 people, 25.00%
Constipation: 4 people, 25.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 25.00%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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