Ibrutinib and Exforge drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ibrutinib (ibrutinib) and Exforge (amlodipine besylate; valsartan). Common drug interactions include cerebrovascular disorder among females and epistaxis among males.

The phase IV clinical study analyzes what interactions people have when they take Ibrutinib and Exforge. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Ibrutinib?

Ibrutinib has active ingredients of ibrutinib. eHealthMe is studying from 13,529 Ibrutinib users. Check the latest studies of Ibrutinib.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

On Jul, 15, 2026

11 people who take Ibrutinib and Exforge together, and have interactions are studied.

Ibrutinib and Exforge drug interactions.

What are the common drug interactions of Ibrutinib and Exforge, by gender? *:

female:

Cerebrovascular disorder (disease of brain)
Febrile neutropenia (fever with reduced white blood cells)
Hypotension (abnormally low blood pressure)
Neutropenia (an abnormally low number of neutrophils)
Pneumonia
Cardiac arrest

male:

Epistaxis (bleed from the nose)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Interstitial lung disease
Pericarditis (inflammation of the pericardium)
Sepsis (a severe blood infection that can lead to organ failure and death)
Large intestinal haemorrhage (bleeding in large intestine)
Pulmonary congestion (congestion in the lungs)
Haematoma (collection of blood outside the blood vessels)
Type 2 diabetes mellitus

What are the common drug interactions of Ibrutinib and Exforge, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Interstitial lung disease
Pericarditis (inflammation of the pericardium)
Sepsis (a severe blood infection that can lead to organ failure and death)
Type 2 diabetes mellitus

60+:

Epistaxis (bleed from the nose)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Haematoma (collection of blood outside the blood vessels)
Cardiac arrest
Cerebrovascular disorder (disease of brain)
Febrile neutropenia (fever with reduced white blood cells)
Hypotension (abnormally low blood pressure)
Large intestinal haemorrhage (bleeding in large intestine)
Neutropenia (an abnormally low number of neutrophils)
Pneumonia

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 63.64%
Diabetes: 4 people, 36.36%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 36.36%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 3 people, 27.27%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 18.18%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 18.18%
Constipation: 2 people, 18.18%
Anaemia (lack of blood): 2 people, 18.18%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 9.09%
Type 2 Diabetes: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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