Ibu and Juluca drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ibu (ibuprofen) and Juluca (dolutegravir sodium; rilpivirine hydrochloride). Common drug interactions include nephropathy among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Ibu and Juluca. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

What is Juluca?

Juluca has active ingredients of dolutegravir sodium; rilpivirine hydrochloride. eHealthMe is studying from 1,732 Juluca users. Check the latest studies of Juluca.

On Aug, 05, 2026

46 people who take Ibu and Juluca together, and have interactions are studied.

What are the common drug interactions of Ibu and Juluca, by gender? *:

female:

Nephropathy (damage to or disease of a kidney)
Rash
Renal disorder (kidney disease)
Renal pain (kidney pain)
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)
Suicidal ideation
Suicide attempt
Tooth fracture
Urethral stenosis (narrowing of the urethra, may cause decreased urine output)

male:

Emotional distress
Anxiety
Multiple fractures
Renal impairment (severely reduced kidney function)
Rib fracture
Tooth disorder (tooth disease)
Tooth loss
Bone loss
Gait disturbance
Osteonecrosis (death of bone)

What are the common drug interactions of Ibu and Juluca, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Quality of life decreased
Bone density decreased
Osteoporosis (bones weak and more likely to break)
Forearm fracture (fracture in between wrist to elbow)
General physical health deterioration (weak health status)
Hyperkalaemia (damage to or disease of the kidney)
Renal failure (kidney dysfunction)

50-59:

Emotional distress
Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Renal failure (kidney dysfunction)
Bone density decreased
Osteoporosis (bones weak and more likely to break)
Tooth loss
Arthralgia (joint pain)
Depression

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Neuropathy peripheral (surface nerve damage)
Renal impairment (severely reduced kidney function)
Bone pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Contusion (a type of hematoma of tissue in which capillaries)
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Gait disturbance

What are the existing conditions these people have? *

Hiv Infection: 43 people, 93.48%
Bacterial Infection: 7 people, 15.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 15.22%
High Blood Pressure: 7 people, 15.22%
Inflammation: 7 people, 15.22%
Hypersensitivity: 5 people, 10.87%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 5 people, 10.87%
Fungal Infection: 5 people, 10.87%
Laxative Supportive Care: 5 people, 10.87%
Stress And Anxiety: 5 people, 10.87%

* Approximation only. Some reports may have incomplete information.

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