1. Home
  2. Analysis
  3. Ibu
  4. Xermelo

Ibu and Xermelo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ibu (ibuprofen) and Xermelo (telotristat etiprate). Common drug interactions include asthenia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Ibu and Xermelo. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

What is Xermelo?

Xermelo has active ingredients of telotristat etiprate. eHealthMe is studying from 2,149 Xermelo users. Check the latest studies of Xermelo.

On Jul, 12, 2026

12 people who take Ibu and Xermelo together, and have interactions are studied.

Ibu and Xermelo drug interactions.

What are the common drug interactions of Ibu and Xermelo, by gender? *:

female:

  1. Asthenia (weakness)
  2. Blood glucose increased
  3. Disease progression
  4. Glycosylated haemoglobin increased
  5. Muscular weakness (muscle weakness)
  6. Neuropathy peripheral (surface nerve damage)
  7. Poor quality sleep
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Fatigue (feeling of tiredness)
  10. Constipation

male:

  1. Fatigue (feeling of tiredness)
  2. Diarrhoea
  3. Oedema peripheral (superficial swelling)
  4. Pain in extremity

What are the common drug interactions of Ibu and Xermelo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Fatigue (feeling of tiredness)
  2. Constipation
  3. Glycosylated haemoglobin increased
  4. Muscular weakness (muscle weakness)
  5. Neuropathy peripheral (surface nerve damage)
  6. Poor quality sleep
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Oedema peripheral (superficial swelling)
  9. Surgery
  10. Tooth extraction

What are the existing conditions these people have? *

  1. Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 7 people, 58.33%
  2. Neuroendocrine Tumor: 2 people, 16.67%
  3. Rectal Cancer (cancer of rectum): 1 person, 8.33%
  4. Neuropathy Peripheral (surface nerve damage): 1 person, 8.33%
  5. Headache (pain in head): 1 person, 8.33%
  6. Diabetes: 1 person, 8.33%
  7. Carcinoid Tumor Pulmonary: 1 person, 8.33%
  8. Carcinoid Tumor Of The Small Bowel: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ibu and Xermelo?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ibu and Xermelo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xermelo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibu and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xermelo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and telotristat etiprate (the active ingredients of Ibu and Xermelo, respectively), and Ibu and Xermelo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.