Ifex and Adriamycin pfs drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ifex (ifosfamide) and Adriamycin pfs (doxorubicin hydrochloride). Common drug interactions include pleural effusion among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Ifex and Adriamycin pfs. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Ifex?

Ifex has active ingredients of ifosfamide. eHealthMe is studying from 829 Ifex users. Check the latest studies of Ifex.

What is Adriamycin pfs?

Adriamycin pfs has active ingredients of doxorubicin hydrochloride. eHealthMe is studying from 6,495 Adriamycin pfs users. Check the latest studies of Adriamycin pfs.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

26 people who take Ifex and Adriamycin pfs together, and have interactions are studied.

Ifex and Adriamycin pfs drug interactions.

What are the common drug interactions of Ifex and Adriamycin Pfs, by gender? *:

female:

Pleural effusion (water on the lungs)
Anxiety
Bone disorder
Bone erosion
Cellulitis (infection under the skin)
Chest wall mass
Decreased interest
Deformity (disfigurement)
Emotional distress
General physical health deterioration (weak health status)

male:

Hypotension (abnormally low blood pressure)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
White blood cell count abnormal
Anaemia (lack of blood)
Body temperature increased
Cough
Cystitis haemorrhagic (blood in the urine and painful voiding)
Haematuria (presence of blood in urine)
Haematuria present (presence of blood in urine due to trauma)
Hypoxia (low oxygen in tissues)

What are the common drug interactions of Ifex and Adriamycin Pfs, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anaemia (lack of blood)
Cystitis haemorrhagic (blood in the urine and painful voiding)
Febrile neutropenia (fever with reduced white blood cells)
White blood cell count abnormal

20-29:

n/a

30-39:

Blood chloride abnormal
Blood potassium abnormal
Blood sodium abnormal
Dehydration (dryness resulting from the removal of water)
Febrile neutropenia (fever with reduced white blood cells)
Haematocrit
Haemoglobin abnormal
Mucosal inflammation (infection of mucous membrane)
Pathological fracture (broken bone caused by disease)
White blood cell count abnormal

40-49:

Body temperature increased
Dyspnoea (difficult or laboured respiration)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Metastases to lung (cancer spreads to lung)
Mucosal inflammation (infection of mucous membrane)
Neutrophil count abnormal (abnormal number of neutrophil a type of blood cell)
Pharyngolaryngeal pain
Pleural effusion (water on the lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory rate increased (excess breathing rate/min)

50-59:

Hypotension (abnormally low blood pressure)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Neutropenia (an abnormally low number of neutrophils)
Pulmonary embolism (blockage of the main artery of the lung)
Acute respiratory distress syndrome
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia fungal
Cough

60+:

Anxiety
Bone disorder
Impaired healing
Metastases to bone (cancer spreads to bone)
Pain
Pleural effusion (water on the lungs)
Sinusitis (inflammation of sinus)
Tooth infection
Pulmonary mass
Tooth extraction

What are the existing conditions these people have? *

Leiomyosarcoma (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue): 10 people, 38.46%

* Approximation only. Some reports may have incomplete information.

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