Ifosfamide and Velcade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ifosfamide (ifosfamide) and Velcade (bortezomib). Common drug interactions include pancytopenia among females and mucosal inflammation among males.

The phase IV clinical study analyzes what interactions people have when they take Ifosfamide and Velcade. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Ifosfamide?

Ifosfamide has active ingredients of ifosfamide. eHealthMe is studying from 21,285 Ifosfamide users. Check the latest studies of Ifosfamide.

What is Velcade?

Velcade has active ingredients of bortezomib. It is often used in multiple myeloma. eHealthMe is studying from 66,422 Velcade users. Check the latest studies of Velcade.

On Jul, 14, 2026

75 people who take Ifosfamide and Velcade together, and have interactions are studied.

Ifosfamide and Velcade drug interactions.

What are the common drug interactions of Ifosfamide and Velcade, by gender? *:

female:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Death
Hypokalaemia (low potassium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Infection
Abdominal pain
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Haemoglobin decreased

male:

Mucosal inflammation (infection of mucous membrane)
Neutropenia (an abnormally low number of neutrophils)
Night sweats (sweating in night)
Death
Dehydration (dryness resulting from the removal of water)
Disease recurrence
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Intracardiac thrombus (presence of a circumscribed mass with heart wall)

What are the common drug interactions of Ifosfamide and Velcade, by age (0-1 to 60+)? *:

0-1:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

2-9:

n/a

10-19:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Nausea (feeling of having an urge to vomit)
Neoplasm malignant (cancer tumour)
Back pain
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Infection

20-29:

Alopecia (absence of hair from areas of the body)
Death
Dizziness
Fatigue (feeling of tiredness)

30-39:

Mucosal inflammation (infection of mucous membrane)
Neutropenia (an abnormally low number of neutrophils)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Asthenia (weakness)
Drug intolerance (drug sensitivity)
General physical condition
Night sweats (sweating in night)
Pyrexia (fever)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

40-49:

Abdominal pain
Haemoglobin decreased
Hypokalaemia (low potassium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Platelet count decreased
Pleural effusion (water on the lungs)
Pleural fibrosis (formation of fibrous tissue in lung)
White blood cell count decreased
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
B-cell lymphoma recurrent (blood cancer affecting b cells-recurrent)

50-59:

Death
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Infection
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Renal impairment (severely reduced kidney function)
Lymphadenopathy (disease or enlargement of lymph nodes)
Neuropathy peripheral (surface nerve damage)
Splenomegaly (enlargement of spleen)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)

60+:

Hepatitis b
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Mantle cell lymphoma (cancer of lymphocytes, a type of white blood cell)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
Plasmablastic lymphoma (aggressive b-cell cancer occurring mainly in the jaws and oral cavity)
Platelet count decreased
Pneumonia
Pyrexia (fever)

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 33 people, 44.00%
Plasmablastic Lymphoma (aggressive b-cell cancer occurring mainly in the jaws and oral cavity): 8 people, 10.67%
Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 6 people, 8.00%
Lymphoma Aids Related (cancer of lymph system with aids): 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

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