Ilaris and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ilaris (canakinumab) and Keppra (levetiracetam). Common drug interactions include pyrexia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Ilaris and Keppra. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Ilaris?

Ilaris has active ingredients of canakinumab. eHealthMe is studying from 13,059 Ilaris users. Check the latest studies of Ilaris.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Jul, 15, 2026

19 people who take Ilaris and Keppra together, and have interactions are studied.

What are the common drug interactions of Ilaris and Keppra, by gender? *:

female:

Pyrexia (fever)
Dyspnoea (difficult or laboured respiration)
Interstitial lung disease
Pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Arthralgia (joint pain)
Back pain
Erythema (redness of the skin)
Eye pruritus (eye itching)

male:

Pyrexia (fever)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Oral candidiasis (fungal infection of mouth)
Papilloedema (optic disc swelling)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Rhinorrhoea (watery mucus discharge from the nose)
Road traffic accident
Subdural hygroma (subdural collection of cerebrospinal fluid (csf), without blood)
Vomiting
White blood cell count increased

What are the common drug interactions of Ilaris and Keppra, by age (0-1 to 60+)? *:

0-1:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
C-reactive protein increased
Carnitine deficiency
Cerebral atrophy (decrement in size of brain)
Constipation
Cough
Decreased appetite
Hyperthermia (body temperature greatly above normal)
Nasopharyngitis (inflammation of the nasopharynx)
Oral candidiasis (fungal infection of mouth)

2-9:

Pyrexia (fever)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Arthralgia (joint pain)
Back pain
Erythema (redness of the skin)
Eye pruritus (eye itching)
Infection
Lacrimation increased
Limb injury
Malaise (a feeling of general discomfort or uneasiness)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dyspnoea (difficult or laboured respiration)
Interstitial lung disease
Pulmonary hypertension (increase in blood pressure in the lung artery)
Chills (felling of cold)
Headache (pain in head)
Pain
Pyrexia (fever)
Viral infection

50-59:

Headache (pain in head)
Muscle rigidity (muscle stiffness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pain

60+:

Amyloidosis (a tumour within which amyloid is produced)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Unresponsive to stimuli
Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Concomitant disease progression (progress in accompanying disease)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Haemorrhage intracranial (bleeding within the skull)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Respiration (transport of oxygen from the outside air to the cells within tissues)

What are the existing conditions these people have? *

Fever: 9 people, 47.37%
Chronic Infantile Neurological Cutaneous And Articular Syndrome (a rare genetic periodic fever with joints inflammation): 7 people, 36.84%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 36.84%
Pneumonia: 6 people, 31.58%
Anaemia (lack of blood): 6 people, 31.58%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 31.58%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 6 people, 31.58%
C-Reactive Protein Increased: 6 people, 31.58%
Constipation: 6 people, 31.58%
Gastroenteritis (inflammation of stomach and intestine): 4 people, 21.05%

* Approximation only. Some reports may have incomplete information.

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