Imdur and Naprosyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imdur (isosorbide mononitrate) and Naprosyn (naproxen). Common drug interactions include gait disturbance among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Imdur and Naprosyn. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Imdur?

Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

On Jul, 10, 2026

85 people who take Imdur and Naprosyn together, and have interactions are studied.

What are the common drug interactions of Imdur and Naprosyn, by gender? *:

female:

Gait disturbance
Muscle spasms (muscle contraction)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Asthenia (weakness)
Burning sensation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug ineffective
Dyspnoea (difficult or laboured respiration)

male:

Dyspnoea (difficult or laboured respiration)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Cellulitis (infection under the skin)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dyslipidaemia (abnormal amount of lipids)

What are the common drug interactions of Imdur and Naprosyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Abscess (pus)
Alcoholic liver disease
Anaemia (lack of blood)
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Anxiety
Arrhythmia (irregular heartbeat)
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Arthralgia (joint pain)
Arthropathy

30-39:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pancreatitis (inflammation of pancreas)
Pancreatitis acute (sudden inflammation of pancreas)
Type 2 diabetes mellitus

40-49:

Pain in extremity
Angina pectoris (chest pain due to ischemia of the heart muscle)
Dyspnoea (difficult or laboured respiration)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Restless legs syndrome (a powerful urge to move your legs)
Anger
Asthma
Attention deficit/hyperactivity disorder
Back disorder
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

50-59:

Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac disorder
Cardiac murmur (an heart sound in valve abnormality)
Carotid bruit (sound heard over the carotid artery area during auscultation)
Cold sweat
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

60+:

Renal failure (kidney dysfunction)
Acute myocardial infarction (acute heart attack)
Myalgia (muscle pain)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Cough

What are the existing conditions these people have? *

High Blood Pressure: 11 people, 12.94%
Bone Disorder: 11 people, 12.94%
Multiple Myeloma (cancer of the plasma cells): 10 people, 11.76%
High Blood Cholesterol: 9 people, 10.59%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.06%
Stress And Anxiety: 5 people, 5.88%
Insomnia (sleeplessness): 5 people, 5.88%
Hypersensitivity: 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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